{"id":"W1990570289","doi":"10.1016/j.stem.2012.02.024","title":"Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem Cells","year":2012,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Biology; Endoderm; Induced pluripotent stem cell; Cell biology; Progenitor cell; Embryonic stem cell; Stem cell; Transplantation; Progenitor; Cellular differentiation; Immunology; Genetics; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000187557,0.0003447735,0.0004881247,0.000101782,0.0001875408,0.00005058641,0.0001238996,0.0001980695,0.0004526857],"category_scores_gemma":[0.000002019438,0.0002921206,0.0001833075,0.0001727776,0.00003292984,0.0001384604,0.0000684163,0.0002146344,0.0009031759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001217007,"about_ca_system_score_gemma":0.0000801596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005291268,"about_ca_topic_score_gemma":9.206733e-7,"domain_scores_codex":[0.9979916,0.0001090327,0.0004952263,0.0003916352,0.0003605662,0.0006519522],"domain_scores_gemma":[0.9986096,0.00009663909,0.0001781285,0.000452082,0.0001218009,0.0005417233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004168326,0.0006709521,0.02088744,0.0002877122,0.0000970863,0.0000219081,0.000779385,0.00001657406,0.9729903,0.000005102676,0.003514412,0.0006874252],"study_design_scores_gemma":[0.002258005,0.0001343268,0.0008768495,0.00004897972,0.0004005278,0.000005191765,0.0004789623,0.0006675036,0.9498963,0.000001540254,0.04493232,0.0002994572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760001,0.005813805,0.00008713744,0.0000331062,0.001382056,0.0005955935,0.00002431771,0.0003519341,0.01571194],"genre_scores_gemma":[0.9773533,0.00006136925,0.001502522,0.0003080849,0.001989688,0.00005361701,0.00009738774,0.00007031334,0.01856376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0414179,"threshold_uncertainty_score":0.9999531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02405984885591141,"score_gpt":0.2274842689449129,"score_spread":0.2034244200890015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}