{"id":"W1990572469","doi":"10.1016/j.mad.2007.12.007","title":"Progressive apoptosis resistance prior to senescence and control by the anti-apoptotic protein BCL-xL","year":2008,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Fonds de Recherche du Québec - Santé","keywords":"Apoptosis; Bcl-xL; Senescence; Biology; Cell biology; Regulator; Programmed cell death; Molecular biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004225194,0.0002219738,0.0002989894,0.0005355885,0.0002161383,0.0008772434,0.0002788109,0.0003856544,0.002092513],"category_scores_gemma":[0.0005878508,0.000225394,0.000274196,0.0002187062,0.0004238809,0.000794791,0.0003220264,0.001138305,0.0005755918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003628254,"about_ca_system_score_gemma":0.0002396114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001715954,"about_ca_topic_score_gemma":0.0001827135,"domain_scores_codex":[0.9997559,0.00004102277,0.00002729247,0.0000482276,0.00006197858,0.00006553719],"domain_scores_gemma":[0.9993203,0.0001396498,0.0002224484,0.0001247011,0.0000757018,0.0001173325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007989749,0.00006148504,0.001157945,0.00005930511,0.00001211714,0.0002268161,0.00006458884,0.00007528902,0.9891924,0.001363861,0.0001457381,0.006841416],"study_design_scores_gemma":[0.000171806,0.0008593339,0.02496843,0.00001841592,0.00003045119,0.001671329,0.00009430608,0.0009241323,0.9638869,0.001098803,0.006262594,0.00001355308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796677,0.01069652,0.005922708,0.0004929638,0.00007321713,0.00002313995,0.000218704,0.000337968,0.002567206],"genre_scores_gemma":[0.9955584,0.001201871,0.0008987148,0.00006969464,0.00002868712,0.00001546433,0.0001592297,0.00001303995,0.002054882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002092513,"threshold_uncertainty_score":0.007000148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211572316617933,"score_gpt":0.2236510787487474,"score_spread":0.2115353555825681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}