{"id":"W1990584179","doi":"10.1210/me.2004-0449","title":"General Receptor for Phosphoinositides 1, a Novel Repressor of Thyroid Hormone Receptor Action that Prevents Deoxyribonucleic Acid Binding","year":2005,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Biology; Transcription factor; Chromatin immunoprecipitation; Receptor; Repressor; Cell biology; Thyroid hormone receptor; Molecular biology; Biochemistry; Promoter; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006278037,0.0002848688,0.0005127261,0.000194773,0.00009341641,0.00001203213,0.0001426086,0.0001547619,0.00008796433],"category_scores_gemma":[0.00007220325,0.0002702858,0.0002832863,0.0001467269,0.00009415442,0.000111668,0.00006443794,0.0001595353,0.00006561475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000146203,"about_ca_system_score_gemma":0.00005194331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007721896,"about_ca_topic_score_gemma":0.00001201658,"domain_scores_codex":[0.9982482,0.00004258601,0.0003782253,0.0005256708,0.0002208762,0.0005844876],"domain_scores_gemma":[0.9990548,0.00003567672,0.0002331111,0.0004561821,0.00009047604,0.0001297512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008841104,0.0007239921,0.002930931,0.00004265429,0.000417232,0.0000165889,0.0001076704,0.00002783902,0.9826434,0.0004371656,0.002283728,0.009484719],"study_design_scores_gemma":[0.007689935,0.001122039,0.003370675,0.00003861196,0.000250194,0.0001273204,0.00008429032,0.0001120316,0.976454,0.00006204247,0.01046483,0.0002240189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891396,0.003807132,0.004409254,0.0009929016,0.0002216565,0.001008299,0.0000887316,0.0001288111,0.000203641],"genre_scores_gemma":[0.9687443,0.0006485523,0.02877637,0.0002902306,0.0001076285,0.0002482514,0.0001932879,0.00008451922,0.0009068675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02436712,"threshold_uncertainty_score":0.9999749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02760672305742169,"score_gpt":0.2938324034211478,"score_spread":0.2662256803637261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}