{"id":"W1990593698","doi":"10.4161/cc.22376","title":"Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biology; Autophagy; Cancer; Cancer research; Mitochondrial biogenesis; Breast cancer; Cancer cell; Biogenesis; Mitochondrion; Organelle biogenesis; Cell biology; Apoptosis; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001613803,0.0002020352,0.0002841709,0.0001931364,0.0001810978,0.0003972926,0.00009677853,0.0002153209,0.0008862667],"category_scores_gemma":[0.0001020209,0.0001026383,0.0002546626,0.0001859054,0.000130743,0.0001291201,0.0001857169,0.0005116169,0.0003529759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002904769,"about_ca_system_score_gemma":0.0002199756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005390995,"about_ca_topic_score_gemma":0.0008678429,"domain_scores_codex":[0.9998617,0.0000297091,0.00001460509,0.00002228137,0.00004188924,0.00002974885],"domain_scores_gemma":[0.9999121,0.00001583653,0.00002697151,0.00001390534,0.00001222757,0.00001891883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001278695,0.00004073902,0.001002072,0.00006452206,0.000008102189,0.00009721788,0.00002019609,0.0001095638,0.9966031,0.0001634034,0.00007668288,0.001686545],"study_design_scores_gemma":[0.00001880446,0.0005145674,0.009208426,0.00001209828,0.00002939416,0.0006040393,0.00007672748,0.001157853,0.9827232,0.0001078983,0.005541806,0.000005154888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98992,0.003503499,0.003521681,0.0003785479,0.00006119682,0.0000496428,0.0004518076,0.0001507908,0.00196285],"genre_scores_gemma":[0.993699,0.002237863,0.001756981,0.0001168092,0.00001105624,0.00003636316,0.0005855308,0.00001139576,0.001545104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008862667,"threshold_uncertainty_score":0.002964854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006928082577910088,"score_gpt":0.2284311167386586,"score_spread":0.2215030341607485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}