{"id":"W1990604167","doi":"10.2174/156800908785699306","title":"Epigenetic Aberrations and Targeted Epigenetic Therapy of Esophageal Cancer","year":2008,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Royal University Hospital","funders":"","keywords":"Epigenetics; Malignancy; Esophageal cancer; Biology; Esophagus; Disease; Epigenetic therapy; Cancer; Cancer research; Carcinogenesis; Somatic evolution in cancer; Bioinformatics; Carcinoma; Medicine; Genetics; Pathology; Internal medicine; Gene; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003485573,0.0006245376,0.00105845,0.001141648,0.0002175973,0.000449843,0.0007416554,0.0009700495,0.001781901],"category_scores_gemma":[0.000287275,0.0001774195,0.0003185849,0.00112066,0.0003037161,0.0007213324,0.0004071817,0.001196356,0.001467461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005210949,"about_ca_system_score_gemma":0.0004196273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006980557,"about_ca_topic_score_gemma":0.001811648,"domain_scores_codex":[0.9998953,0.00001971883,0.00001072234,0.00001680613,0.00004613978,0.00001122036],"domain_scores_gemma":[0.9999359,0.0000225788,0.00001117097,0.000002820194,0.00001920228,0.000008360877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000953461,0.0001003254,0.0001984543,0.004582568,0.0000691482,0.000691216,0.00004971569,0.0004961784,0.006616709,0.002674846,0.02098215,0.9634434],"study_design_scores_gemma":[0.0000477069,0.0002252317,0.001466013,0.0009358097,0.00007461986,0.005160253,0.00005051738,0.000228853,0.003034432,0.001812945,0.9869466,0.0000170532],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004437428,0.9973495,0.000297041,0.0003058727,0.0001947237,0.000006269024,0.000009910834,0.00001013968,0.001382809],"genre_scores_gemma":[0.001783804,0.9959656,0.0003328638,0.0002551262,0.00014248,0.000009568149,0.00002333049,0.000001743204,0.001485323],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001781901,"threshold_uncertainty_score":0.005961061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04657069195341299,"score_gpt":0.3657157121025971,"score_spread":0.3191450201491841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}