{"id":"W1990606334","doi":"10.1128/jvi.00353-08","title":"Differential Antigen Requirements for Protection against Systemic and Intranasal Vaccinia Virus Challenges in Mice","year":2008,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Vaccinia; Virology; Biology; Virus; Smallpox vaccine; Antigen; Nasal administration; Immune system; Neutralizing antibody; Poxviridae; Viral vector; Immunization; Immunology; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003348512,0.0001204887,0.0003766798,0.0002800373,0.0001083694,0.000004588504,0.0001554768,0.000266961,0.00003122584],"category_scores_gemma":[0.0001092825,0.00009809138,0.00007418745,0.00004693492,0.000118196,0.0001101699,0.00004166852,0.000389604,0.00001195581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004567199,"about_ca_system_score_gemma":0.00006898313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002921094,"about_ca_topic_score_gemma":0.0000994997,"domain_scores_codex":[0.9987241,0.0002762162,0.0004534508,0.0001617043,0.00004321812,0.0003413042],"domain_scores_gemma":[0.9994568,0.00009776789,0.0002441034,0.00008213537,0.00008115309,0.00003802421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002493893,0.0001308045,0.001382916,0.00004308805,0.0001593306,0.00004997443,0.0004492085,0.000002939599,0.9815001,0.00003556558,0.0002339389,0.0135182],"study_design_scores_gemma":[0.03069742,0.01106349,0.256817,0.0003640909,0.0001212664,0.01291529,0.0007044156,0.00016459,0.6604944,0.0008479011,0.02509768,0.0007124512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883913,0.00981475,0.0003802956,0.000571573,0.0004645838,0.0002992656,0.00001075467,0.000007298583,0.00006017834],"genre_scores_gemma":[0.9823201,0.0174148,0.00002977118,0.00005248652,0.00011115,0.00001518711,0.000004298793,0.00001061593,0.00004162338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3210057,"threshold_uncertainty_score":0.400005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06665555007015041,"score_gpt":0.2896896207175234,"score_spread":0.223034070647373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}