{"id":"W1990606491","doi":"10.1002/cmdc.200700063","title":"Mannosylated G(0) Dendrimers with Nanomolar Affinities to <i>Escherichia coli</i> FimH","year":2007,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Wetenschappelijk Onderzoek","keywords":"Canavalia ensiformis; Chemistry; Pentaerythritol; Escherichia coli; Dendrimer; Concanavalin A; Stereochemistry; Propargyl; Lectin; Sonogashira coupling; Mannose; Tetramer; Biochemistry; Combinatorial chemistry; In vitro; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106393,0.000325655,0.0001337577,0.00009947007,0.00008913216,0.0001511434,0.0001985543,0.0002459689,0.0005115679],"category_scores_gemma":[0.000132531,0.00008908288,0.0001098616,0.0001049761,0.0001444349,0.0001406469,0.0001574322,0.000235808,0.000286151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003265236,"about_ca_system_score_gemma":0.0001196303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004521049,"about_ca_topic_score_gemma":0.0009372945,"domain_scores_codex":[0.9999373,0.00001035133,0.00000440461,0.00001301641,0.0000119784,0.00002305541],"domain_scores_gemma":[0.9999392,0.00001103144,0.0000168384,0.000005976603,0.00001112926,0.00001590977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002476312,0.000003650506,0.00003740585,0.000009361457,0.000001382698,0.00001081361,0.000004781232,0.00007309922,0.999089,0.00003877416,0.00001839537,0.0006885316],"study_design_scores_gemma":[0.000005601715,0.0001572667,0.0006242363,0.000001565178,0.000006875223,0.0000652677,0.000005455502,0.0002786063,0.9977016,0.00001489729,0.001136461,0.000002158927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991174,0.0006771281,0.0060244,0.00006602893,0.00001540927,0.00005028392,0.0001031222,0.0001058469,0.001783855],"genre_scores_gemma":[0.9887627,0.0004211872,0.00814214,0.00007115516,0.000008307936,0.00003331898,0.0002281188,0.00002300546,0.002310112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005115679,"threshold_uncertainty_score":0.002369165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094986510229451,"score_gpt":0.2123666941328841,"score_spread":0.2014168290305896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}