{"id":"W1990606491","doi":"10.1002/cmdc.200700063","title":"Mannosylated G(0) Dendrimers with Nanomolar Affinities to <i>Escherichia coli</i> FimH","year":2007,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Wetenschappelijk Onderzoek","keywords":"Canavalia ensiformis; Chemistry; Pentaerythritol; Escherichia coli; Dendrimer; Concanavalin A; Stereochemistry; Propargyl; Lectin; Sonogashira coupling; Mannose; Tetramer; Biochemistry; Combinatorial chemistry; In vitro; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002492711,0.0004387833,0.0004063134,0.00006515408,0.0001646609,0.00007615479,0.0004367038,0.0002941706,0.002117422],"category_scores_gemma":[0.0001077218,0.000416912,0.0001366044,0.0004661668,0.0001608725,0.0001156982,0.0001002876,0.000358638,0.0002076849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001822031,"about_ca_system_score_gemma":0.0001017263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003793222,"about_ca_topic_score_gemma":0.00003079967,"domain_scores_codex":[0.9978075,0.000007517885,0.0004035488,0.0005856395,0.0003922318,0.0008035715],"domain_scores_gemma":[0.9984112,0.0002023529,0.0001266312,0.0006522529,0.0001334855,0.0004740535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002885294,0.0001061596,0.0005283835,0.0001531585,0.0001141176,0.0001794085,0.000615869,0.000007796644,0.9946519,0.00004532065,0.002391797,0.0009175744],"study_design_scores_gemma":[0.0005334649,0.00002384975,0.00008899509,0.0001085411,0.00006569676,0.00003712847,0.001502053,0.00001014163,0.9580305,0.00002475009,0.03899117,0.0005836826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8014343,0.0001234071,0.00008852653,0.0002130478,0.00006233532,0.000078565,0.00002690353,0.0002290684,0.1977439],"genre_scores_gemma":[0.9858984,0.00001253349,0.001461117,0.0005729513,0.0002872605,0.00003833478,0.00006914124,0.00008712145,0.01157308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1861708,"threshold_uncertainty_score":0.9998283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094986510229451,"score_gpt":0.2123666941328841,"score_spread":0.2014168290305896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}