{"id":"W1990641349","doi":"10.1073/pnas.0604777104","title":"Modern origin of numerous alternatively spliced human introns from tandem arrays","year":2007,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Genome Canada","keywords":"Intron; Biology; Group II intron; Human genome; Genetics; Genome; Gene duplication; RNA splicing; Gene; Tandem repeat; Group I catalytic intron; Tandem exon duplication; Coding region; Computational biology; Evolutionary biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009637985,0.00006769055,0.0001090943,0.00007594014,0.0001089784,0.000009000533,0.0006375921,0.000069474,0.000005735704],"category_scores_gemma":[0.0002254148,0.00004760735,0.00006014654,0.0002112067,0.0004946121,0.00001767457,0.0001262514,0.00009868342,3.097666e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001437773,"about_ca_system_score_gemma":0.0000302293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005296134,"about_ca_topic_score_gemma":0.00000118965,"domain_scores_codex":[0.9987167,0.000004298339,0.0002447166,0.000194957,0.0006856612,0.0001537368],"domain_scores_gemma":[0.9994342,0.00003247132,0.0002879584,0.00001003747,0.0001970696,0.00003827772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002024636,0.00002684918,0.01254329,0.000008387728,0.00002091986,4.298112e-9,0.00005711949,0.00003233655,0.9812008,0.005652673,0.000105519,0.0003318242],"study_design_scores_gemma":[0.0001839289,0.00007475584,0.04615656,0.00002645396,0.000004094787,0.000001098892,0.00008993458,0.0003811884,0.9381382,0.01479497,0.00009864753,0.00005013532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965367,0.0001055558,0.0001187022,0.00035154,0.000007249323,0.0000911485,0.00001550951,0.000002297641,0.002771305],"genre_scores_gemma":[0.9979855,0.00002068511,0.001592649,0.00006727744,0.0001095036,0.00000220056,6.204448e-7,0.000003409478,0.0002181312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0430626,"threshold_uncertainty_score":0.1941371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04542376562172124,"score_gpt":0.3497091593212256,"score_spread":0.3042853936995044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}