{"id":"W1990675342","doi":"10.1038/nprot.2007.203","title":"Use of luminescent bacteria for rapid screening and characterization of short cationic antimicrobial peptides synthesized on cellulose using peptide array technology","year":2007,"lang":"en","type":"article","venue":"Nature Protocols","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Peptide; Antimicrobial; Combinatorial chemistry; Antimicrobial peptides; Bacteria; Cellulose; High-throughput screening; Luminescence; Biology; Chemistry; Biochemistry; Microbiology; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003544292,0.0002394118,0.0005018233,0.0003363163,0.0001328739,0.00002256488,0.0001515876,0.0006949474,0.00002177824],"category_scores_gemma":[0.0001543485,0.0002194967,0.0001152074,0.0001939695,0.0003441318,0.0002004517,0.00005217679,0.0003613428,0.000001153442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003104543,"about_ca_system_score_gemma":0.00005456185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000186429,"about_ca_topic_score_gemma":0.000007877898,"domain_scores_codex":[0.9986944,0.00006193333,0.0005363884,0.0003333829,0.00004374011,0.0003301672],"domain_scores_gemma":[0.9988769,0.0002016599,0.0004094893,0.0002499307,0.0002431771,0.00001887333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001443904,0.0001798291,0.003409628,0.000266747,0.0001000944,7.957934e-7,0.00009063389,0.00000194226,0.9894984,0.0003377528,0.00007420066,0.004596036],"study_design_scores_gemma":[0.0008064433,0.0002791083,0.007209349,0.0007345019,0.00004912919,0.00002761546,0.00003841391,0.000008031853,0.9861792,0.00001189819,0.00445482,0.0002015381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739943,0.00002731227,0.006559971,0.00009140042,0.0001170369,0.01899354,0.0001532846,0.00004434423,0.00001882792],"genre_scores_gemma":[0.9888684,0.000009611634,0.009519744,0.00006431781,0.00005205201,0.001120012,0.0001573175,0.0000339848,0.0001746018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01787353,"threshold_uncertainty_score":0.8950815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02942664617116186,"score_gpt":0.2882189491454035,"score_spread":0.2587923029742417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}