{"id":"W1990771269","doi":"10.1002/jmr.606","title":"Kinetic analysis of the interactions between Troponin C (TnC) and Troponin I (TnI) binding peptides: evidence for separate binding sites for the ‘structural’ N‐terminus and the ‘regulatory’ C‐terminus of TnI on TnC","year":2003,"lang":"en","type":"article","venue":"Journal of Molecular Recognition","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of General Medical Sciences","keywords":"Chemistry; Troponin I; Troponin C; Biophysics; Dissociation constant; Ternary complex; Stereochemistry; Biochemistry; Receptor; Enzyme; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007814748,0.0006348956,0.0007629055,0.0001789829,0.0003093584,0.0005119204,0.0008190821,0.0005261347,0.001439481],"category_scores_gemma":[0.001186476,0.0003573825,0.0005827572,0.0002718984,0.0004151675,0.0006244903,0.0003415416,0.001064861,0.0006419188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007485517,"about_ca_system_score_gemma":0.0003334418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002660608,"about_ca_topic_score_gemma":0.001637321,"domain_scores_codex":[0.9993304,0.00009930902,0.00002510164,0.0001596173,0.0002484089,0.0001372013],"domain_scores_gemma":[0.999074,0.0003901789,0.0001633653,0.00005018487,0.0001711412,0.0001510602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003851973,0.00009518198,0.001424922,0.0001319998,0.00005321524,0.00005313573,0.0001081826,0.0009019998,0.9941028,0.000302125,0.0001012431,0.002340105],"study_design_scores_gemma":[0.00005813982,0.0004394525,0.01558729,0.00002278217,0.00005900697,0.0003714625,0.00009940771,0.03873239,0.9424632,0.0002078076,0.001902986,0.00005607699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850445,0.002494547,0.0101433,0.0001045431,0.00003447547,0.00007508015,0.000228627,0.00004626758,0.001828546],"genre_scores_gemma":[0.9872472,0.001067153,0.008514429,0.00007794461,0.00001359865,0.00007596336,0.000622277,0.00003056223,0.002350821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002660608,"threshold_uncertainty_score":0.005431116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06398777681073407,"score_gpt":0.3444083893570928,"score_spread":0.2804206125463587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}