{"id":"W1990786456","doi":"10.1126/science.1181348","title":"Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins","year":2010,"lang":"en","type":"article","venue":"Science","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":505,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Chromosome segregation; Biology; Anaphase; Gene; Chromosome; Cell division; Genetics; Cell biology; RNA; RNA interference; Computational biology; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004686812,0.00007615146,0.0001709724,0.0001752322,0.0001504496,0.0000472251,0.0003625396,0.00005078154,0.00001878744],"category_scores_gemma":[0.0001473785,0.00006458544,0.00007999902,0.0006340985,0.0004107247,0.00001022203,0.00009458189,0.00005259049,0.000002727783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006703584,"about_ca_system_score_gemma":0.00006744295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003627725,"about_ca_topic_score_gemma":0.0004006205,"domain_scores_codex":[0.9991414,0.00002183685,0.0002274908,0.0002553615,0.0002096124,0.0001443328],"domain_scores_gemma":[0.9992628,0.000003754277,0.0001608906,0.0003616704,0.0001692349,0.00004170174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000001231006,0.00002528294,0.0003431155,0.0003037305,0.00005141696,1.677409e-7,0.00005961515,0.00001057702,0.9984192,0.0007689659,0.000004243746,0.00001250327],"study_design_scores_gemma":[0.00005791617,0.00005487801,0.003797827,0.00009486234,0.00008899788,0.00000146962,0.00004887507,0.0004151387,0.9952064,0.0001383116,0.00001243901,0.00008289715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986618,0.00004408248,0.0005887593,0.00001240148,0.0000500169,0.0004490397,0.0000114339,0.000007039789,0.0001753925],"genre_scores_gemma":[0.9989174,0.00000176995,0.0005484668,0.00001153667,0.00002043644,0.00004681054,0.00002235009,0.000004239757,0.0004269695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003454711,"threshold_uncertainty_score":0.2633718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007838013116511607,"score_gpt":0.26364260384822,"score_spread":0.2558045907317084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}