{"id":"W1990792003","doi":"10.1007/s00018-008-8429-z","title":"Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program","year":2008,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Bone health and treatments","field":"Medicine","cited_by":470,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"RUNX2; Adipogenesis; Mesenchymal stem cell; Cell biology; Wnt signaling pathway; Biology; Adipocyte; Osteoblast; Bone marrow; Cellular differentiation; Stem cell; Transcription factor; Endocrinology; Signal transduction; Adipose tissue; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417866,0.0004144729,0.001206642,0.0001632115,0.0003588961,0.00004998373,0.0001860567,0.0002019232,0.00001658985],"category_scores_gemma":[0.00001476488,0.0002161952,0.0003485822,0.0005376523,0.001039408,0.00006305658,0.0000796262,0.0002542261,0.00000685148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003402306,"about_ca_system_score_gemma":0.0008421757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005288228,"about_ca_topic_score_gemma":0.00001053746,"domain_scores_codex":[0.9975635,0.0001922435,0.0005362759,0.0005981004,0.0006595878,0.000450227],"domain_scores_gemma":[0.9986166,0.00005996782,0.0005022347,0.0003869483,0.00009823962,0.0003360154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000185393,0.0008352314,0.0004248084,0.02072939,0.001094207,0.0008529219,0.0004565227,0.000006119489,0.003145893,0.00008329808,0.0001893286,0.9719969],"study_design_scores_gemma":[0.004526026,0.006437898,0.0004136016,0.01087173,0.005870296,0.0018476,0.0002779939,0.000209961,0.02469074,0.00001271422,0.9435437,0.001297748],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06376428,0.933677,0.00009449641,0.00006409258,0.0001116564,0.002020223,0.00001579544,0.00003547442,0.000217009],"genre_scores_gemma":[0.05239915,0.9464745,0.0004258346,0.00008230195,0.00002965733,0.0001847508,0.00005120222,0.00003637313,0.0003162442],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9706991,"threshold_uncertainty_score":0.8816185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03156490337326817,"score_gpt":0.3092216247954997,"score_spread":0.2776567214222315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}