{"id":"W1990834285","doi":"10.1182/blood-2003-02-0660","title":"Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"","keywords":"Lipopolysaccharide; In vivo; Tumor necrosis factor alpha; Proinflammatory cytokine; Cytokine; Genetic enhancement; Transgene; Biology; Sepsis; Immunology; Pharmacology; Inflammation; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002130866,0.0004418793,0.0002192678,0.0001322611,0.00008150479,0.000310622,0.0001793057,0.0002606575,0.001007773],"category_scores_gemma":[0.0001471823,0.00008608148,0.0001678199,0.000104361,0.0004283863,0.0002318623,0.0001600437,0.0007791682,0.0002221146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001644565,"about_ca_system_score_gemma":0.0002586709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001794705,"about_ca_topic_score_gemma":0.0001056174,"domain_scores_codex":[0.9999092,0.00002294312,0.000007020222,0.00002170881,0.00001800469,0.000021119],"domain_scores_gemma":[0.9999317,0.00001876012,0.00002209966,0.00001003351,0.000003926661,0.00001347239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003419704,0.0001083062,0.0001470083,0.00008230341,0.000008742628,0.0000548283,0.00001865857,0.00008454786,0.9906069,0.0003237825,0.00009036806,0.008132516],"study_design_scores_gemma":[0.0001980136,0.003110956,0.003271488,0.00001820926,0.00003949598,0.0007132229,0.00002541707,0.001180642,0.9848036,0.0002727045,0.006357199,0.000009059849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659502,0.0111112,0.01904638,0.0005146656,0.0001840662,0.0001224366,0.0002811553,0.0003558518,0.002434205],"genre_scores_gemma":[0.9853468,0.005014778,0.007174287,0.0001225096,0.00006411699,0.00006606364,0.0003864538,0.00002021741,0.001804754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001007773,"threshold_uncertainty_score":0.003371298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008647960250619499,"score_gpt":0.1993672197451148,"score_spread":0.1907192594944953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}