{"id":"W1990840993","doi":"10.1093/nar/gkt918","title":"High-copy bacterial plasmids diffuse in the nucleoid-free space, replicate stochastically and are randomly partitioned at cell division","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Minority Health and Health Disparities; National Institute of Allergy and Infectious Diseases; Wellcome Trust","keywords":"Plasmid; Biology; Cell division; Nucleoid; T-DNA Binary system; Genetics; Caulobacter crescentus; Origin of replication; Cell biology; Gene; Escherichia coli; Cell; Cell cycle; Vector (molecular biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007620251,0.0002054377,0.0002426454,0.0001153702,0.0003946764,0.0001411955,0.0007159198,0.0004619387,0.0002177562],"category_scores_gemma":[0.0003770003,0.0001467346,0.00005510907,0.0002214558,0.000552158,0.000009238019,0.001490143,0.0003895512,0.0001085851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003077971,"about_ca_system_score_gemma":0.0000381176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001136021,"about_ca_topic_score_gemma":0.0001051342,"domain_scores_codex":[0.9977548,0.0003224191,0.0002973073,0.0006312914,0.0003764304,0.000617828],"domain_scores_gemma":[0.9984895,0.00009554627,0.00007385514,0.001043215,0.000163242,0.0001346178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005752068,0.0001820308,0.001302183,0.00001973103,0.00001236766,0.000006399611,0.00007080408,0.000002403654,0.9889184,0.0002207128,0.007998994,0.0006907799],"study_design_scores_gemma":[0.01408666,0.002600244,0.1551021,0.0000602641,0.00002205413,0.0000339554,0.0003536461,0.0002896717,0.7713877,0.003624908,0.05176962,0.0006691372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924706,0.0001098097,0.00008469744,0.006072077,0.0001164964,0.0007609611,0.00004896323,0.00001860796,0.0003178025],"genre_scores_gemma":[0.9979857,0.0004215404,0.000488773,0.0001604978,0.000237583,0.0001563444,0.00006526622,0.00003538677,0.0004488582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2175307,"threshold_uncertainty_score":0.5983662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628034214167023,"score_gpt":0.2647283452051548,"score_spread":0.2484480030634846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}