{"id":"W1990840993","doi":"10.1093/nar/gkt918","title":"High-copy bacterial plasmids diffuse in the nucleoid-free space, replicate stochastically and are randomly partitioned at cell division","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Minority Health and Health Disparities; National Institute of Allergy and Infectious Diseases; Wellcome Trust","keywords":"Plasmid; Biology; Cell division; Nucleoid; T-DNA Binary system; Genetics; Caulobacter crescentus; Origin of replication; Cell biology; Gene; Escherichia coli; Cell; Cell cycle; Vector (molecular biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983536,0.0003422691,0.0003635254,0.0003615651,0.0002621281,0.0005979112,0.0002451205,0.0003038038,0.0006903],"category_scores_gemma":[0.0004149479,0.0002576618,0.0002383519,0.0003366959,0.000475716,0.0003899362,0.0004859016,0.0004356333,0.000605059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003255699,"about_ca_system_score_gemma":0.0003284421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006105432,"about_ca_topic_score_gemma":0.000780508,"domain_scores_codex":[0.9996814,0.00006992637,0.00001548746,0.00009559232,0.00009936815,0.00003829475],"domain_scores_gemma":[0.9996779,0.00009349219,0.00009601546,0.00005722988,0.00003282433,0.00004261985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000951141,0.0000265752,0.003046423,0.00006807384,0.00001835065,0.00009313505,0.00006096847,0.0008373602,0.9903999,0.0008316389,0.00004029213,0.004482169],"study_design_scores_gemma":[0.00003514206,0.000361049,0.02103413,0.00002938801,0.00004147553,0.0009865067,0.000181857,0.010661,0.959865,0.001435791,0.005331751,0.00003698823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583245,0.001786371,0.03844596,0.00006200597,0.00001382637,0.00004420717,0.0001342954,0.0001245854,0.001064287],"genre_scores_gemma":[0.9903733,0.0005925227,0.007352185,0.00002412982,0.000006254642,0.00004695883,0.0003239143,0.00002140856,0.001259369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006903,"threshold_uncertainty_score":0.002362251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628034214167023,"score_gpt":0.2647283452051548,"score_spread":0.2484480030634846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}