{"id":"W1990852009","doi":"10.1074/jbc.c000291200","title":"Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"AMPK; Internal medicine; Endocrinology; Malonyl-CoA; Skeletal muscle; Chemistry; Activator (genetics); Phosphatase; Protein kinase A; AMP-activated protein kinase; Phosphorylation; Biochemistry; Enzyme; Biology; Beta oxidation; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004363221,0.0002109258,0.0004055499,0.00002413526,0.00004956686,0.0000218685,0.000190884,0.0003224984,0.0001640616],"category_scores_gemma":[0.0003495136,0.0001365307,0.0001548188,0.0001220378,0.0003102573,0.00002172418,0.00003393407,0.0003409979,7.036574e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003818408,"about_ca_system_score_gemma":0.00006738983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002404083,"about_ca_topic_score_gemma":0.000002203644,"domain_scores_codex":[0.9985981,0.0001672991,0.0005612144,0.0002486469,0.0001862387,0.0002385097],"domain_scores_gemma":[0.999051,0.0000744755,0.0004512268,0.0001968204,0.0001201538,0.0001063704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001258968,0.0001553323,0.0002636666,0.00003096478,0.00005006198,0.000003283498,0.0000206625,0.00001961291,0.9665125,0.000003021408,0.0001688186,0.03151308],"study_design_scores_gemma":[0.002914476,0.0001195521,0.001618425,0.00005532351,0.00002210859,0.00001917394,0.00005528714,0.00001039205,0.9583909,0.00007227312,0.03656355,0.0001585426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841856,0.01521844,0.00002600883,0.0001101729,0.00004539157,0.0002115651,0.00001867374,0.000004653086,0.0001794641],"genre_scores_gemma":[0.9922722,0.007134736,0.00005704534,0.0001376971,0.0002375452,0.00002412668,0.00004204093,0.00001292986,0.00008169751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03639473,"threshold_uncertainty_score":0.556756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0094516278811509,"score_gpt":0.2298274096365882,"score_spread":0.2203757817554373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}