{"id":"W1990914940","doi":"10.1074/jbc.m212992200","title":"Heterogeneity in Control of mRNA Stability by AU-rich Elements","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"AU-rich element; Messenger RNA; Untranslated region; Biology; P-bodies; Three prime untranslated region; Molecular biology; Context (archaeology); Cell biology; Translation (biology); Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009369245,0.0001090003,0.0002620742,0.00001354912,0.00002218841,0.000006177632,0.0002105595,0.0001820109,0.0000747582],"category_scores_gemma":[0.0008439692,0.00007785999,0.0001278106,0.00006965395,0.0001054484,0.000003281511,0.00003518618,0.0001986174,5.173652e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004575162,"about_ca_system_score_gemma":0.0001148151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005493087,"about_ca_topic_score_gemma":0.000002980664,"domain_scores_codex":[0.9987483,0.0001313749,0.0005239968,0.0001659272,0.0001669477,0.0002634283],"domain_scores_gemma":[0.9992779,0.00003630933,0.0002563964,0.0001604775,0.0001340075,0.0001348369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001609858,0.0001574661,0.2683595,0.0000163173,0.00002926197,0.000004590889,0.000002605474,0.000004039605,0.7309976,9.284878e-7,0.00009710983,0.0001696493],"study_design_scores_gemma":[0.001179558,0.0003405082,0.007370614,0.00001054298,0.000004344329,0.00002471644,0.00004739008,0.000006785754,0.9897128,0.00002933299,0.001194014,0.00007937424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982026,0.0009041388,0.000332489,0.00003715198,0.00002341192,0.00005995751,0.00002219257,0.000001071693,0.0004169698],"genre_scores_gemma":[0.9994976,0.0001665352,0.0001766682,0.00004688928,0.00005027048,0.000002277744,0.000009137501,0.000004319219,0.0000463066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2609889,"threshold_uncertainty_score":0.3175038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02224474514299074,"score_gpt":0.2892490005431835,"score_spread":0.2670042554001927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}