{"id":"W1990960245","doi":"10.1016/j.virol.2007.01.011","title":"Immunogenicity of papaya mosaic virus-like particles fused to a hepatitis C virus epitope: Evidence for the critical function of multimerization","year":2007,"lang":"en","type":"article","venue":"Virology","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame; Armand Frappier Museum; Institut National de la Recherche Scientifique; Hôpital Saint-Luc; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immunogenicity; Epitope; Virology; Biology; Capsid; Antigen; Virus; Virus-like particle; Antibody; Immune system; Hepatitis C virus; Recombinant DNA; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002613604,0.0000766572,0.0001212725,0.00002283453,0.00006993157,0.000003336442,0.0001400686,0.0001010007,0.00001792403],"category_scores_gemma":[0.0002090387,0.00006157604,0.00006872804,0.00008954955,0.0001410234,0.000004278702,0.00003101776,0.00003794447,0.000003545977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004501353,"about_ca_system_score_gemma":0.00002678934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003796038,"about_ca_topic_score_gemma":0.001124976,"domain_scores_codex":[0.9992728,0.00003758796,0.0002660884,0.0001884551,0.00006491756,0.0001701943],"domain_scores_gemma":[0.9993039,0.0002496245,0.00006692327,0.0002540361,0.00008590888,0.00003960743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006633719,0.00007769526,0.00144405,0.00001154497,0.00004699995,1.751765e-7,0.00004521681,0.00009966063,0.9880846,0.0003583122,0.0001865654,0.008981866],"study_design_scores_gemma":[0.0003289063,0.0005468397,0.1076373,0.000007041036,0.00008323517,0.000003207823,0.00001567257,0.0003573495,0.8816503,0.0001163015,0.009176418,0.00007735609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7535617,0.0006748494,0.244989,0.0002533876,0.00008638963,0.0002566304,0.0001693237,0.00000507418,0.000003634266],"genre_scores_gemma":[0.9975707,0.0004913641,0.001346342,0.0003839245,0.00006437243,0.0000696721,0.00005462001,0.00000883675,0.00001018949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.244009,"threshold_uncertainty_score":0.2510998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03211432222148979,"score_gpt":0.3188101761918102,"score_spread":0.2866958539703204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}