{"id":"W1991102295","doi":"10.1111/j.1538-7836.2008.03183.x","title":"Apolipoprotein(a) inhibits the conversion of Glu‐plasminogen to Lys‐plasminogen: a novel mechanism for lipoprotein(a)‐mediated inhibition of plasminogen activation","year":2008,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Plasmin; Lipoprotein(a); Chemistry; Apolipoprotein B; Plasminogen activator; Biochemistry; Fibrin; Kringle domain; Lipoprotein; Fibrinolysis; Mutant; Tissue plasminogen activator; Molecular biology; Enzyme; Biology; Internal medicine; Cholesterol; Immunology; Endocrinology; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005077025,0.0002589988,0.0005058253,0.0001967358,0.0002093966,0.00001574761,0.0002122269,0.0002660191,0.00001634889],"category_scores_gemma":[0.0003040885,0.0001988093,0.0002928663,0.0002196026,0.0001268987,0.00004062273,0.0001430867,0.0001400362,0.000001532097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003690743,"about_ca_system_score_gemma":0.0001726313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008638373,"about_ca_topic_score_gemma":0.00001021066,"domain_scores_codex":[0.9981266,0.00006617412,0.0007979427,0.0002840081,0.0004523851,0.0002728509],"domain_scores_gemma":[0.9977617,0.00006274085,0.0009537332,0.00028589,0.0007686802,0.0001672708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007219803,0.000210579,0.00007863628,0.0001189828,0.0002441174,0.000001037224,0.0003472741,0.00001722783,0.9956705,0.0003054156,0.001542722,0.0007415261],"study_design_scores_gemma":[0.002273282,0.002227491,0.0003386267,0.0002113739,0.0001366009,0.00007014132,0.0003123264,0.00006755063,0.9928246,0.0002857937,0.001039377,0.0002129067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881213,0.0001970068,0.009563331,0.0007664593,0.000151622,0.0009438021,0.0002120411,0.000005040113,0.00003942296],"genre_scores_gemma":[0.9933177,0.0005481086,0.005335577,0.0004030978,0.0002439585,0.00004490489,0.00004978347,0.00003325655,0.00002365956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005196378,"threshold_uncertainty_score":0.8107209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04313705476585026,"score_gpt":0.2710015379048694,"score_spread":0.2278644831390192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}