{"id":"W1991102295","doi":"10.1111/j.1538-7836.2008.03183.x","title":"Apolipoprotein(a) inhibits the conversion of Glu‐plasminogen to Lys‐plasminogen: a novel mechanism for lipoprotein(a)‐mediated inhibition of plasminogen activation","year":2008,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Plasmin; Lipoprotein(a); Chemistry; Apolipoprotein B; Plasminogen activator; Biochemistry; Fibrin; Kringle domain; Lipoprotein; Fibrinolysis; Mutant; Tissue plasminogen activator; Molecular biology; Enzyme; Biology; Internal medicine; Cholesterol; Immunology; Endocrinology; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003896767,0.0004381498,0.0002443609,0.0003106739,0.0001962156,0.0006185981,0.0004183567,0.0005482924,0.001472334],"category_scores_gemma":[0.0003463556,0.0002215976,0.0004321363,0.0001226884,0.0003116193,0.000250606,0.0001922948,0.0005341812,0.0007336522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003534698,"about_ca_system_score_gemma":0.0002468332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004480665,"about_ca_topic_score_gemma":0.0003235012,"domain_scores_codex":[0.9998354,0.00003692137,0.00001603787,0.00002534876,0.0000425494,0.00004373963],"domain_scores_gemma":[0.9997981,0.00005956298,0.00003921251,0.00003150111,0.00002840172,0.00004320965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000919872,0.0002089257,0.000766265,0.00005392484,0.00003972727,0.0005045857,0.00002459788,0.00007496912,0.9889529,0.001031533,0.0003018511,0.007120823],"study_design_scores_gemma":[0.0002782101,0.0009656253,0.007124769,0.000006974697,0.00006822046,0.001604388,0.00001944394,0.001553846,0.9842474,0.0006827473,0.00343452,0.00001393093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801312,0.003360756,0.01144038,0.0003608695,0.0002422341,0.00005349476,0.0001333414,0.0002903,0.003987343],"genre_scores_gemma":[0.9944949,0.0007386429,0.002014354,0.0001295803,0.00005605744,0.00002476754,0.0001014033,0.00001956734,0.002420746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001472334,"threshold_uncertainty_score":0.00492543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04313705476585026,"score_gpt":0.2710015379048694,"score_spread":0.2278644831390192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}