{"id":"W1991109477","doi":"10.1007/s12079-011-0125-3","title":"CCN2: a bona fide target for anti-fibrotic drug intervention","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Fibrosis; Mediator; In vivo; Connective tissue; CTGF; Medicine; Transforming growth factor; Growth factor; Drug; Pathology; Cancer research; Bioinformatics; Immunology; Pharmacology; Biology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006674497,0.0004764964,0.000527742,0.0003458112,0.0004296336,0.0007717638,0.0005973411,0.002907596,0.002716996],"category_scores_gemma":[0.0007952005,0.0001045045,0.0002158835,0.00017363,0.0009907576,0.001227559,0.0003369035,0.002282668,0.0009788447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006606807,"about_ca_system_score_gemma":0.0007199977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003592392,"about_ca_topic_score_gemma":0.001976788,"domain_scores_codex":[0.999681,0.00006818927,0.00002476192,0.00005573919,0.0001375079,0.00003274064],"domain_scores_gemma":[0.9996235,0.0001290206,0.000030244,0.00001007734,0.0001231229,0.00008394256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005112867,0.00006599233,0.0004434178,0.002085555,0.00003767585,0.00207695,0.0001796486,0.0003685594,0.0582794,0.02365865,0.6995587,0.2127343],"study_design_scores_gemma":[0.00003487318,0.0001768076,0.0004830164,0.0003012063,0.00002165345,0.001345825,0.0001117716,0.0003017036,0.007466739,0.005809539,0.9839262,0.00002054104],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0074937,0.5359436,0.005611444,0.3087147,0.1267637,0.00005075499,0.0002409584,0.0001911755,0.01498997],"genre_scores_gemma":[0.07821205,0.5665681,0.007867482,0.115152,0.1583013,0.0001210015,0.0002382136,0.0001184142,0.07342134],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002907596,"threshold_uncertainty_score":0.009089231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0336169290875271,"score_gpt":0.2914005371272239,"score_spread":0.2577836080396968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}