{"id":"W1991109477","doi":"10.1007/s12079-011-0125-3","title":"CCN2: a bona fide target for anti-fibrotic drug intervention","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Fibrosis; Mediator; In vivo; Connective tissue; CTGF; Medicine; Transforming growth factor; Growth factor; Drug; Pathology; Cancer research; Bioinformatics; Immunology; Pharmacology; Biology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000742349,0.00006517116,0.0001136219,0.00006668905,0.00008290527,0.00002320435,0.0002267447,0.00004202898,0.00005272671],"category_scores_gemma":[0.0001200473,0.00006036133,0.0001027975,0.00003781158,0.00004062314,0.00001113015,0.00008808164,0.0001168974,0.000001025133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000988536,"about_ca_system_score_gemma":0.00002844302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001295918,"about_ca_topic_score_gemma":0.000005101424,"domain_scores_codex":[0.9993228,0.0001500309,0.0002660142,0.00007952024,0.0000837097,0.00009795519],"domain_scores_gemma":[0.9992188,0.00005673687,0.0002219578,0.0001940471,0.000249676,0.00005876692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002276734,0.0001381458,0.003448174,0.00007102161,0.00005503975,0.000001066693,0.0006299693,0.00001274169,0.9929254,0.0001438563,0.0004322503,0.001914658],"study_design_scores_gemma":[0.00119864,0.0004687658,0.002832704,0.00008198518,0.00002584298,0.00002078053,0.0005867182,0.0001932884,0.9855828,0.001747838,0.007148659,0.0001120342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800668,0.004178722,0.01497241,0.0000849705,0.00003374513,0.000129767,0.000002770422,0.000002411299,0.000528379],"genre_scores_gemma":[0.9889927,0.0002964819,0.01041636,0.00002520174,0.00004159961,0.000004277037,0.0000123463,0.00001049927,0.0002005304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008925883,"threshold_uncertainty_score":0.2461464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0336169290875271,"score_gpt":0.2914005371272239,"score_spread":0.2577836080396968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}