{"id":"W1991163865","doi":"10.1007/s100720070011","title":"Gene transfer in skeletal muscle by systemic injection of DODAC lipopolyplexes","year":2000,"lang":"en","type":"article","venue":"Neurological Sciences","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Inimex Pharmaceuticals (Canada)","funders":"Fondazione Telethon","keywords":"Transfection; Genetic enhancement; Systemic administration; Skeletal muscle; Luciferase; Reporter gene; Gene transfer; In vivo; Cell biology; Chemistry; Gene; Molecular biology; Biophysics; Medicine; Biology; Pharmacology; Gene expression; Biochemistry; Anatomy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001549609,0.00007933655,0.0001026256,0.00002689081,0.0000446274,0.0000109033,0.0002135313,0.00009930795,0.0001338246],"category_scores_gemma":[0.00001588292,0.00005771085,0.00005215488,0.0001485392,0.0002227707,0.000006179888,0.00001790108,0.00006061083,0.000009613662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002238086,"about_ca_system_score_gemma":0.00001553077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005083862,"about_ca_topic_score_gemma":0.00004406212,"domain_scores_codex":[0.9991643,0.00007345645,0.0001701582,0.0002977777,0.0001189941,0.0001753464],"domain_scores_gemma":[0.9998365,0.00001079146,0.00001705196,0.00008997414,0.00001340376,0.00003228366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003316405,0.00006424997,0.01034169,0.000003463272,0.000002221508,0.0000022406,0.00001757635,0.0003507129,0.9738299,0.000007955454,0.0002393812,0.01510747],"study_design_scores_gemma":[0.0006504335,0.00862092,0.05988228,0.00001779121,0.00001088489,0.0001300223,0.00006388341,0.0004904362,0.9225727,0.0001697046,0.007041216,0.0003497624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983313,0.0006883702,0.00003449371,0.00008995747,0.00005988465,0.00007353754,0.000007962052,0.000006508958,0.0007079737],"genre_scores_gemma":[0.9990065,0.0005019412,0.00002773098,0.0002835656,0.00004154519,0.000007668964,0.000006484884,0.000002431759,0.0001221925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0512572,"threshold_uncertainty_score":0.235338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01113056950341213,"score_gpt":0.2355796518511771,"score_spread":0.2244490823477649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}