{"id":"W1991189794","doi":"10.1038/cdd.2008.67","title":"The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death","year":2008,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":332,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Associazione Italiana per la Ricerca sul Cancro; Vetenskapsrådet; Fondation de France; Ministero della Salute; Institut National de la Santé et de la Recherche Médicale; Natural Sciences and Engineering Research Council of Canada; European Commission","keywords":"Calreticulin; Anthracycline; Immunogenic cell death; Cell biology; Endoplasmic reticulum; Apoptosis; Biology; Cancer cell; Immunogenicity; Small hairpin RNA; Cancer research; Programmed cell death; Immune system; Gene knockdown; Molecular biology; Cancer; Biochemistry; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008667666127076756,"score_gpt":0.2202481094416863,"score_spread":0.2115804433146095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["observational","bench_or_experimental"],"consensus_intersection":["observational","bench_or_experimental"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.0001373311970702678,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0,"bibliometrics":0.000015259021896696422,"sts":0.00015259021896696422,"scholarly_communication":0.000030518043793392844,"open_science":0.000015259021896696422,"research_integrity":0.00012207217517357137,"randomized_trial":0.00010681315327687495,"nonrandomized_trial":0.000030518043793392844,"observational":0.41370260166323336,"systematic_review":0.000015259021896696422,"meta_analysis":0.00022888532845044633,"case_report":0.000045777065690089265,"qualitative":0.00010681315327687495,"simulation_or_modeling":0.00015259021896696422,"bench_or_experimental":0.8017395284962234,"theoretical_or_conceptual":0.000289921416037232,"not_applicable":0.00039673456931410697,"design_other":0.0009002822919050889},"gemma":{"metaresearch":0.00006103608758678569,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0.000015259021896696422,"bibliometrics":0,"sts":0.0003662165255207141,"scholarly_communication":0,"open_science":0.000015259021896696422,"research_integrity":0.00022888532845044633,"randomized_trial":0.00007629510948348211,"nonrandomized_trial":0.00009155413138017853,"observational":0.28120851453421836,"systematic_review":0,"meta_analysis":0.00006103608758678569,"case_report":0.000030518043793392844,"qualitative":0.00006103608758678569,"simulation_or_modeling":0.001083390554665446,"bench_or_experimental":0.9149919890135042,"theoretical_or_conceptual":0.00030518043793392844,"not_applicable":0.0003509575036240177}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}