{"id":"W1991217148","doi":"10.1021/bi061754e","title":"Insights into S100 Target Specificity Examined by a New Interaction between S100A11 and Annexin A2","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Annexin A2; Annexin; Chemistry; Peptide; Exocytosis; Phosphatidylserine; Annexin A1; Binding site; Biochemistry; Biophysics; Stereochemistry; Membrane; Phospholipid; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000572664,0.0002574525,0.0001929589,0.00003061155,0.0001056148,0.0000615965,0.0001741834,0.0003002818,0.00005387036],"category_scores_gemma":[0.00004121361,0.0002550007,0.00007613579,0.00009334453,0.00009448123,0.000009584095,0.0001271018,0.0001374979,0.00001222035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003245448,"about_ca_system_score_gemma":0.00007012083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004213862,"about_ca_topic_score_gemma":0.00002145369,"domain_scores_codex":[0.9987651,0.00002574039,0.0002651076,0.0005686285,0.0001327817,0.0002426726],"domain_scores_gemma":[0.999314,0.00001183354,0.0001116684,0.0003502307,0.00005144229,0.0001608581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005269967,0.00006043668,0.003086663,0.00002788464,0.00002578397,0.00000291985,0.0000177759,0.000001690121,0.9570804,0.00001675715,0.03832304,0.00130395],"study_design_scores_gemma":[0.0004548673,0.0001035987,0.002657157,0.00001974332,0.00001219723,0.000006017404,0.00006338664,0.00001717117,0.8931624,0.0003232983,0.1028875,0.0002927569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919197,0.002848092,0.001561905,0.0001717401,0.00007528345,0.0001325248,0.00003014625,0.00003531038,0.003225301],"genre_scores_gemma":[0.991562,0.00006791306,0.00104472,0.00009255996,0.001402495,0.00001291776,0.0009067034,0.00003025537,0.004880428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06456441,"threshold_uncertainty_score":0.9999902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007912326691865989,"score_gpt":0.2274167328043595,"score_spread":0.2195044061124936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}