{"id":"W1991291838","doi":"10.1016/j.bpj.2010.07.047","title":"Quantitative Experimental Assessment of Macromolecular Crowding Effects at Membrane Surfaces","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Vesicle; Biophysics; Maltose-binding protein; Chemistry; Dihydrofolate reductase; Membrane; Lipid bilayer; Liposome; Receptor–ligand kinetics; Phosphatidylethanolamine; Macromolecular crowding; Biochemistry; Macromolecule; Phospholipid; Fusion protein; Phosphatidylcholine; Biology; Recombinant DNA; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001101393,0.0001670189,0.000214059,0.00003238175,0.0001249676,0.0000299033,0.0001911518,0.000113706,0.00006458747],"category_scores_gemma":[0.0000278882,0.0001321828,0.0001953022,0.0000607516,0.0001493105,0.000007674357,0.0001114351,0.0002452458,0.000004459178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001456007,"about_ca_system_score_gemma":0.00005693421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004713287,"about_ca_topic_score_gemma":0.000002827256,"domain_scores_codex":[0.9990372,0.00006469041,0.0002144697,0.0002187704,0.0002454616,0.0002193864],"domain_scores_gemma":[0.9994211,0.0000212734,0.0001502897,0.0001898352,0.00008073594,0.0001368164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007671514,0.0001590495,0.0006432622,0.00001987152,0.0000601035,0.00002432044,0.000035179,0.000009391627,0.9985096,0.0002792253,0.0000612279,0.0001219907],"study_design_scores_gemma":[0.0006430878,0.0006815707,0.005012353,0.00001282374,0.00003887668,0.0001214571,0.00003610335,0.00005501352,0.9928423,0.00000425651,0.0003909641,0.0001611524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986591,0.00002783497,0.0001495301,0.00003255466,0.0006931302,0.0001058406,0.000009567882,0.000005591259,0.0003168706],"genre_scores_gemma":[0.9961737,0.00001304958,0.003254429,0.00004656436,0.0003859663,0.000004552344,0.00001765674,0.00001993336,0.00008411432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005667322,"threshold_uncertainty_score":0.539026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008800717135109147,"score_gpt":0.307243585502799,"score_spread":0.2984428683676898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}