{"id":"W1991291838","doi":"10.1016/j.bpj.2010.07.047","title":"Quantitative Experimental Assessment of Macromolecular Crowding Effects at Membrane Surfaces","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Vesicle; Biophysics; Maltose-binding protein; Chemistry; Dihydrofolate reductase; Membrane; Lipid bilayer; Liposome; Receptor–ligand kinetics; Phosphatidylethanolamine; Macromolecular crowding; Biochemistry; Macromolecule; Phospholipid; Fusion protein; Phosphatidylcholine; Biology; Recombinant DNA; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001100639,0.0005128234,0.0003730567,0.0003676676,0.0004662308,0.0004824536,0.0006509151,0.000729389,0.001541945],"category_scores_gemma":[0.002263761,0.0002353722,0.0001987257,0.0004016455,0.0009400438,0.0005298366,0.000673323,0.0008578659,0.0002292272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008693297,"about_ca_system_score_gemma":0.0003585976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001383524,"about_ca_topic_score_gemma":0.0009063373,"domain_scores_codex":[0.9991493,0.0001818447,0.00004185763,0.000131374,0.0003585961,0.0001370545],"domain_scores_gemma":[0.9975568,0.00149149,0.0001914877,0.0002620888,0.0003794809,0.00011865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007825149,0.00003684475,0.0001945633,0.00003830415,0.000004651418,0.00001346502,0.00003257612,0.0006859033,0.9975531,0.0002081733,0.00003091135,0.001123282],"study_design_scores_gemma":[0.000009440989,0.00009898928,0.001013443,0.000002549756,0.000004725456,0.00001618845,0.00002936674,0.008995241,0.9895419,0.00008463683,0.0001963084,0.000007225126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756232,0.0005133375,0.02150358,0.0001006926,0.00002679171,0.00009753885,0.0003630068,0.00009270593,0.001679301],"genre_scores_gemma":[0.989801,0.0004075741,0.008609949,0.00004717608,0.0000242262,0.0001571293,0.0002997257,0.00002936432,0.000623873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001541945,"threshold_uncertainty_score":0.006307483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008800717135109147,"score_gpt":0.307243585502799,"score_spread":0.2984428683676898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}