{"id":"W1991333388","doi":"10.1038/srep05903","title":"Carbohydrate-Based Ice Recrystallization Inhibitors Increase Infectivity and Thermostability of Viral Vectors","year":2014,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Infectivity; Potency; Biology; Thermostability; Vesicular stomatitis virus; Virus; Freeze-drying; Virology; Chemistry; Biochemistry; Chromatography; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000189952,0.0004377692,0.000238769,0.0001670774,0.0000833887,0.0003539123,0.0002147589,0.0001801241,0.0008311931],"category_scores_gemma":[0.0001865257,0.0001042167,0.0002798911,0.0001019432,0.0001580646,0.0002662445,0.0001788551,0.0005874531,0.0002442708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002301995,"about_ca_system_score_gemma":0.0002015728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005949498,"about_ca_topic_score_gemma":0.00108408,"domain_scores_codex":[0.9998697,0.00002002987,0.00001247082,0.00002313186,0.00004351271,0.00003113785],"domain_scores_gemma":[0.9998442,0.00003052448,0.00006642172,0.00001776017,0.00002276739,0.00001828394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004335895,0.00001531792,0.000135499,0.00002596116,0.000005415562,0.0000108821,0.000008630703,0.00009371716,0.9981081,0.00006120118,0.00001856727,0.001473291],"study_design_scores_gemma":[0.00000344754,0.0001717796,0.001055025,0.000004679064,0.00001064791,0.00004548017,0.00000537606,0.0003001276,0.9972903,0.0000119258,0.001099051,0.000002142007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866182,0.003110823,0.007231554,0.00008693995,0.00002887682,0.00006201266,0.0003098741,0.0001315326,0.002420154],"genre_scores_gemma":[0.9857135,0.002196609,0.008156738,0.0000669983,0.00001223403,0.00004539908,0.0006359754,0.0000712839,0.003101214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008311931,"threshold_uncertainty_score":0.002780616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008843826254629468,"score_gpt":0.2558897142473178,"score_spread":0.2470458879926883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}