{"id":"W1991389998","doi":"10.1091/mbc.e08-06-0603","title":"Microtubule-mediated Src Tyrosine Kinase Trafficking in Neuronal Growth Cones","year":2008,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Yale University; National Institutes of Health; McGill University; Purdue University; Howard Hughes Medical Institute","keywords":"Filopodia; Growth cone; Cell biology; Biology; Proto-oncogene tyrosine-protein kinase Src; Nocodazole; Microtubule; Endocytic cycle; Endosome; Tyrosine kinase; Lamellipodium; Kinase; Cytoskeleton; Endocytosis; Signal transduction; Biochemistry; Axon; Actin; Cell; Intracellular","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001043403,0.0001587575,0.0001738674,0.0000655213,0.00007290325,0.000003706423,0.0003178441,0.000176435,0.00002937767],"category_scores_gemma":[0.00008954024,0.0001307324,0.000169307,0.0001421917,0.0001708782,0.000002173736,0.0001668418,0.0001622134,0.000008465138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001094076,"about_ca_system_score_gemma":0.00006298953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006669063,"about_ca_topic_score_gemma":0.00002944292,"domain_scores_codex":[0.9989944,0.0001389542,0.0002592236,0.000303478,0.00006706851,0.000236844],"domain_scores_gemma":[0.9994094,0.00001664176,0.0001218221,0.00033507,0.00007355227,0.00004347234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004029693,0.0001342348,0.0014943,0.00001006887,0.00001737732,0.00001106195,0.00002527357,0.00004247658,0.9975492,0.0001836308,0.0004416708,0.00005039365],"study_design_scores_gemma":[0.0005923837,0.0001766862,0.001292293,0.00001024026,0.00001082958,0.00003899434,0.00001313629,0.0001188498,0.9913718,0.00008574615,0.006150448,0.0001386079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961435,0.00137811,0.001182732,0.0002707224,0.0002867388,0.000170698,0.00002698629,0.000007074923,0.00053347],"genre_scores_gemma":[0.9985982,0.0001968427,0.0002323072,0.0005560232,0.00003982885,0.00001041948,0.0001240544,0.00002144394,0.0002208833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00617743,"threshold_uncertainty_score":0.5331113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007512858586043233,"score_gpt":0.2162592754836557,"score_spread":0.2087464168976124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}