{"id":"W1991459610","doi":"10.1007/s004010000230","title":"The developmental and aging changes of Down's syndrome cell adhesion molecule expression in normal and Down's syndrome brains","year":2000,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Down syndrome and intellectual disability research","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Blot; Cell adhesion molecule; Biology; Purkinje cell; Cerebellum; Down syndrome; Immunohistochemistry; Endocrinology; Internal medicine; Cell biology; Immunology; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001625032,0.0001673327,0.0001802645,0.0009399545,0.0002379141,0.0003391361,0.0002485529,0.0001874572,0.001340098],"category_scores_gemma":[0.0003185637,0.0001983513,0.0001320246,0.0002213991,0.0003241536,0.0004193771,0.0002467501,0.0002740499,0.0001634579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003051632,"about_ca_system_score_gemma":0.0002116794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001830842,"about_ca_topic_score_gemma":0.001511781,"domain_scores_codex":[0.9999177,0.00001147787,0.00001065977,0.00001387877,0.00001887302,0.00002743186],"domain_scores_gemma":[0.9998295,0.0000477567,0.00002777382,0.00001304766,0.00003039766,0.00005149312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001190914,0.00005270032,0.01206291,0.00005696943,0.00003505175,0.001372695,0.0002583547,0.00009727901,0.9778569,0.0008494571,0.0001743567,0.005992381],"study_design_scores_gemma":[0.00005076079,0.0004451816,0.7021182,0.00001793817,0.0001006571,0.006692346,0.001118017,0.001085563,0.2835063,0.0007498292,0.004090434,0.00002468663],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979862,0.0009114121,0.0001691647,0.00001827761,0.00000713275,0.000002738006,0.0001263622,0.000007361266,0.0007714387],"genre_scores_gemma":[0.9974372,0.0007869279,0.0002116554,0.00001433341,0.000007226608,0.00001171168,0.0002236107,0.000005480972,0.001301755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001830842,"threshold_uncertainty_score":0.004483044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02227564338401867,"score_gpt":0.263883524480219,"score_spread":0.2416078810962003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}