{"id":"W1991466774","doi":"10.1016/j.ydbio.2012.04.022","title":"Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation","year":2012,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Sunnybrook Health Science Centre; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Eye Institute; Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center; National Cancer Institute; National Institutes of Health; Eli Lilly and Company; U.S. Department of Veterans Affairs","keywords":"Biology; Islet; Cell biology; Angiogenesis; Endocrinology; Vascular endothelial growth factor; Internal medicine; Vascular endothelial growth factor A; Cellular differentiation; Cell growth; Endothelial stem cell; Insulin; Cancer research; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003969095,0.0003690837,0.0003825482,0.0004286969,0.000206402,0.0006738719,0.0003068071,0.0004823088,0.001390672],"category_scores_gemma":[0.0002584831,0.0003049931,0.0003914454,0.0002782845,0.0005108614,0.0004165094,0.0002650892,0.00132247,0.0003826257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005646179,"about_ca_system_score_gemma":0.0004309745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008039174,"about_ca_topic_score_gemma":0.0006559376,"domain_scores_codex":[0.9994997,0.0001084043,0.00007266778,0.00008286838,0.0001065156,0.0001298128],"domain_scores_gemma":[0.9994773,0.0001080674,0.0001372373,0.00006737566,0.00002782065,0.0001822126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000162517,0.00004887606,0.00009674406,0.00001138173,0.000004061611,0.00002684524,0.000007641653,0.00005925859,0.9990059,0.0001661424,0.00001791219,0.0003927281],"study_design_scores_gemma":[0.00002493457,0.0002750345,0.001292155,0.000002505469,0.00001167455,0.0001653599,0.0000196074,0.0008044142,0.9962602,0.00006086943,0.001079865,0.000003484535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953211,0.000685651,0.002556059,0.0001181407,0.00006833653,0.0000188155,0.0002009802,0.00008750483,0.0009434687],"genre_scores_gemma":[0.9944028,0.0004379947,0.002690471,0.00006680402,0.00002702055,0.00002622225,0.000331736,0.00004241582,0.00197461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001390672,"threshold_uncertainty_score":0.004652262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009753866773571512,"score_gpt":0.2349062657392189,"score_spread":0.2251523989656473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}