{"id":"W1991588393","doi":"10.1038/npp.2012.259","title":"A Randomized Exploratory Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) for Cognitive Enhancement in Schizophrenia","year":2012,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":175,"is_retracted":false,"has_abstract":false,"ca_institutions":"Columbia College","funders":"","keywords":"Partial agonist; Risperidone; Clinical Global Impression; Schizophrenia (object-oriented programming); Psychology; Randomized controlled trial; Placebo; Internal medicine; Population; Olanzapine; Medicine; Psychiatry; Agonist; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001534405,0.0003551077,0.0008110764,0.0001420385,0.00007389774,0.00001039843,0.0003466938,0.0002440189,0.0001963151],"category_scores_gemma":[0.0006100949,0.0003453876,0.0003079213,0.0001939418,0.0003143665,0.00002141627,0.00013784,0.0002713455,0.00004249981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000269003,"about_ca_system_score_gemma":0.0001698767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005096158,"about_ca_topic_score_gemma":0.000008134555,"domain_scores_codex":[0.9962789,0.001278891,0.000949197,0.0006438693,0.0001904493,0.0006586969],"domain_scores_gemma":[0.9984581,0.0003302085,0.0004641547,0.0003429224,0.0001807539,0.0002238584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5044889,0.001872469,0.00005599364,0.00002112551,0.0001378255,2.477617e-7,0.0001630364,0.00000172409,0.4883498,0.00002504435,0.00169389,0.00318996],"study_design_scores_gemma":[0.6655756,0.002482386,0.00003397793,0.00001342861,0.0001407204,0.00000403266,0.0001132502,0.00002546944,0.3226399,0.00001486019,0.008664133,0.0002922965],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903993,0.0008019152,0.0004335826,0.0001349859,0.004010471,0.00371934,0.00004911748,0.00003025258,0.0004210087],"genre_scores_gemma":[0.9938917,0.0006640568,0.0008663216,0.0007494103,0.001649408,0.001746905,0.0001307413,0.00009688839,0.0002045475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1657099,"threshold_uncertainty_score":0.9998998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02436259943087335,"score_gpt":0.3459506556657624,"score_spread":0.321588056234889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}