{"id":"W1991673453","doi":"10.1016/j.bbapap.2004.11.020","title":"Changing the metal ion selectivity of rabbit muscle enolase by mutagenesis: effects of the G37A and G41A mutations","year":2004,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Concordia University","funders":"Concordia University","keywords":"Chemistry; Divalent; Active site; Mutant; Enolase; Selectivity; Mutagenesis; Wild type; Catalysis; Site-directed mutagenesis; Biochemistry; Stereochemistry; Biophysics; Biology; Gene; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004255011,0.0007490765,0.0005671692,0.0002850977,0.0003537728,0.000565047,0.0007716792,0.0009118167,0.001619064],"category_scores_gemma":[0.0006926173,0.000443107,0.000502714,0.0003207781,0.0007597042,0.0004066109,0.000442154,0.0008575653,0.0007151152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008808584,"about_ca_system_score_gemma":0.0006827462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004791502,"about_ca_topic_score_gemma":0.003182936,"domain_scores_codex":[0.9995814,0.0000846667,0.0001075261,0.00008451293,0.00007860721,0.00006329521],"domain_scores_gemma":[0.9995235,0.0001475544,0.0001212385,0.00006261684,0.00006278224,0.00008225337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000361386,0.00004391016,0.0002355504,0.00003155051,0.00001707146,0.0001476404,0.00003799235,0.0002105207,0.9979256,0.0002231657,0.00003668538,0.0007288036],"study_design_scores_gemma":[0.00003336753,0.00007953526,0.0005626308,0.000004683234,0.0000256172,0.0002716799,0.0000273151,0.0007002491,0.9973894,0.00006586922,0.000828927,0.00001078006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947537,0.0004335133,0.003280229,0.0002751746,0.00007917294,0.00004714342,0.0002735381,0.0001102837,0.0007472443],"genre_scores_gemma":[0.9961058,0.0002885223,0.002298106,0.0000841173,0.000008626789,0.00001511639,0.00015523,0.00009954058,0.0009447444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004791502,"threshold_uncertainty_score":0.009527206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003932235552973938,"score_gpt":0.2034167763678237,"score_spread":0.1994845408148497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}