{"id":"W1991728702","doi":"10.1007/s00239-002-2434-x","title":"The Evolution of Enzyme Specificity in Fasciola spp.","year":2003,"lang":"en","type":"article","venue":"Journal of Molecular Evolution","topic":"Helminth infection and control","field":"Veterinary","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Fasciola; Fasciola hepatica; Cathepsin L; Gene duplication; Fasciola gigantica; Genetics; Enzyme; Cathepsin; Gene; Biochemistry; Evolutionary biology; Zoology; Helminths","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001345384,0.0000998973,0.0001981668,0.0001894024,0.00007719859,0.00001746698,0.0001347179,0.00009436229,0.0000680669],"category_scores_gemma":[0.0005555465,0.0000758763,0.0001955649,0.000282557,0.00006184108,0.0001415596,0.00001372872,0.0002963864,0.00002790782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006029567,"about_ca_system_score_gemma":0.0001798062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007558402,"about_ca_topic_score_gemma":0.00003448047,"domain_scores_codex":[0.998219,0.0005032184,0.0006399922,0.00009817097,0.0003465665,0.0001930113],"domain_scores_gemma":[0.9989706,0.00007533791,0.0004459682,0.0001878303,0.000259496,0.00006081288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009701073,0.0004467069,0.01688888,0.00002602621,0.0001206765,0.0002208119,0.0001986777,0.001859322,0.8746851,0.100509,0.001322813,0.002751922],"study_design_scores_gemma":[0.01241353,0.006020172,0.6901705,0.0006299227,0.0002945905,0.005613403,0.004704738,0.008739918,0.09506534,0.06088198,0.1143361,0.001129783],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9018643,0.002495363,0.08949349,0.0002046918,0.0005954028,0.0001361247,0.000001625836,0.000008060975,0.005200893],"genre_scores_gemma":[0.9995931,0.00003716518,0.0001874742,0.00002367519,0.00007140203,0.000002525921,2.448158e-7,0.000009753951,0.00007465416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7796198,"threshold_uncertainty_score":0.3094146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01764946960749944,"score_gpt":0.2734568923140971,"score_spread":0.2558074227065976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}