{"id":"W1991765333","doi":"10.1111/j.1474-9726.2009.00539.x","title":"Generation of pluripotent stem cells from eggs of aging mice","year":2009,"lang":"en","type":"article","venue":"Aging Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Biology; Homeobox protein NANOG; Embryonic stem cell; Telomere; Induced pluripotent stem cell; Stem cell; Senescence; Cell biology; Rex1; Telomerase; Chimera (genetics); Genetics; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003327537,0.0004573024,0.0001985509,0.0003731001,0.0001382994,0.0002046085,0.0003033364,0.0003247602,0.002319376],"category_scores_gemma":[0.0001994519,0.0003220955,0.0002644024,0.0001516207,0.0001914488,0.0002817014,0.0002788143,0.0005246839,0.001073037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001271981,"about_ca_system_score_gemma":0.0001490156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001429895,"about_ca_topic_score_gemma":0.000298972,"domain_scores_codex":[0.9998437,0.00001938982,0.00003755747,0.00003523867,0.00004631532,0.00001775865],"domain_scores_gemma":[0.9998285,0.00003458776,0.00004983925,0.00003216072,0.00002306389,0.00003179577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003992949,0.00001242669,0.0002480881,0.0000421088,0.000005512411,0.00009594888,0.00002671964,0.00004391423,0.996428,0.0003303271,0.00007897689,0.002648228],"study_design_scores_gemma":[0.00004453574,0.0003301906,0.007720362,0.00002827464,0.00003726467,0.001020923,0.00003246159,0.0005839905,0.9656333,0.0002338483,0.02432276,0.00001204617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8848934,0.005044026,0.09023377,0.0003637378,0.0002436627,0.0009565328,0.005424784,0.0008433993,0.01199666],"genre_scores_gemma":[0.8926671,0.006743968,0.06205495,0.000264433,0.00007142759,0.0009193214,0.008757411,0.0003765917,0.02814473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002319376,"threshold_uncertainty_score":0.007759035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0226836634267479,"score_gpt":0.2694877116056978,"score_spread":0.2468040481789499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}