{"id":"W1991768673","doi":"10.1111/j.1524-4725.2010.01705.x","title":"Multicenter, Randomized, Parallel-Group Study of the Safety and Effectiveness of OnabotulinumtoxinA and Hyaluronic Acid Dermal Fillers (24-mg/mL Smooth, Cohesive Gel) Alone and in Combination for Lower Facial Rejuvenation","year":2010,"lang":"en","type":"article","venue":"Dermatologic Surgery","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Allergan","keywords":"Medicine; Adverse effect; Facial rejuvenation; Hyaluronic acid; Randomized controlled trial; Botulinum toxin; Regimen; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00104798,0.0002041885,0.0009899924,0.000155826,0.00009470936,0.000007265309,0.00006216067,0.0002816207,0.000006714306],"category_scores_gemma":[0.001283692,0.0001303782,0.0001345981,0.0001798333,0.0005332543,0.00007979087,0.00007270461,0.0003550409,2.30559e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001278353,"about_ca_system_score_gemma":0.0000318064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002892938,"about_ca_topic_score_gemma":0.00005525574,"domain_scores_codex":[0.9979508,0.0007038744,0.0006060763,0.0003341309,0.0001860662,0.0002190528],"domain_scores_gemma":[0.9958417,0.003527234,0.0003043597,0.0001697837,0.00009244338,0.00006448888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1774781,0.003597904,0.7967646,0.001063601,0.0003731794,0.00009795897,0.00113557,0.00008343153,0.01308094,0.0004218738,0.00005199324,0.005850851],"study_design_scores_gemma":[0.1326731,0.0003916313,0.8601674,0.000145446,0.0002245719,0.00009516017,0.0004328528,0.003356229,0.001701151,0.0005393361,0.00007634875,0.0001967185],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955977,0.0005425306,0.00009299829,0.0006566498,0.000354673,0.002691617,0.000009378155,0.00001962176,0.00003479952],"genre_scores_gemma":[0.99889,0.000705611,0.00005545791,0.0001996777,0.0000056462,0.0001087903,0.0000177962,0.00001322995,0.000003800205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06340287,"threshold_uncertainty_score":0.5316668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070954040964311,"score_gpt":0.2406099104518592,"score_spread":0.2299003700422161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}