{"id":"W1991829627","doi":"10.1002/dvdy.20292","title":"Ectopic expression of Kit<sup>D814Y</sup> in spermatids of transgenic mice, interferes with sperm morphogenesis","year":2005,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México","keywords":"Spermiogenesis; Biology; Ectopic expression; Cell biology; Spermatid; Transgene; Germ cell; Genetically modified mouse; Spermatogenesis; Molecular biology; Genetics; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000490309,0.0001472639,0.000186311,0.00008236412,0.00001871667,0.000003731453,0.0001621436,0.0001326364,0.00003317833],"category_scores_gemma":[0.000003519954,0.0001159694,0.00005868981,0.0001335075,0.00008634414,0.00000680917,0.0000477411,0.00007583382,0.00000270891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006978418,"about_ca_system_score_gemma":0.0000997167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003830349,"about_ca_topic_score_gemma":0.0002368531,"domain_scores_codex":[0.9991779,0.00002255302,0.0003138499,0.0002004345,0.0001222783,0.0001629845],"domain_scores_gemma":[0.9997281,0.000005054433,0.00008053774,0.0001115522,0.00003242051,0.00004229057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003397718,0.0001210115,0.02613236,0.0001102538,0.00008417376,0.000002987467,0.0006260091,0.005412956,0.9572098,0.00002170839,0.00007235286,0.009866569],"study_design_scores_gemma":[0.001076646,0.0001519912,0.009710995,0.0001991809,0.00001512682,0.00003169197,0.0005205957,0.001768189,0.9856352,0.000006649589,0.0006718271,0.0002119086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978979,0.0003209153,0.000394982,0.00003563641,0.00002997336,0.000123201,0.00003442518,0.0000043696,0.001158608],"genre_scores_gemma":[0.9953237,0.0004549848,0.003645524,0.00003860079,0.00002592497,0.00000796154,0.0001524606,0.00001687893,0.0003339241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02842535,"threshold_uncertainty_score":0.4729095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003568882872743884,"score_gpt":0.194211287506446,"score_spread":0.1906424046337021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}