{"id":"W1991881405","doi":"10.1016/j.neuron.2007.07.033","title":"Use ‘em and Lose ‘em—Activity-Induced Removal of Calcium Channels from the Plasma Membrane","year":2007,"lang":"en","type":"letter","venue":"Neuron","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Membrane; Calcium; Biophysics; Chemistry; Plasma; Voltage-dependent calcium channel; Neuroscience; Cell biology; Psychology; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204047,0.0002539802,0.0002282293,0.00006372712,0.0000716132,0.00004675575,0.0001446696,0.0007629606,0.00002421238],"category_scores_gemma":[0.0001050538,0.0002016482,0.0001159479,0.00007736568,0.00005813157,0.000006946834,0.00009611848,0.0005383065,0.00000657141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000010988,"about_ca_system_score_gemma":0.00003366358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009699935,"about_ca_topic_score_gemma":0.0000261451,"domain_scores_codex":[0.9986999,0.000146266,0.000206762,0.000463016,0.0002570199,0.0002270369],"domain_scores_gemma":[0.9991326,0.00009734969,0.0002007944,0.0004398663,0.00008564509,0.00004378231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004011031,0.00004091035,0.00002754983,0.00005332204,0.00009033709,0.000127942,0.0001247265,0.00004206426,0.7187043,0.000002538,0.2713228,0.009062388],"study_design_scores_gemma":[0.0004877989,0.000225718,0.001264608,0.00002570161,0.00005376334,0.00008315669,0.0000192417,0.0003813331,0.3778423,0.000006657825,0.6193634,0.0002463614],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769766,0.00007714215,0.0002071217,0.02028383,0.001958568,0.0002559977,0.00009073914,0.00001504483,0.0001349291],"genre_scores_gemma":[0.8356912,0.0001373799,0.00006438629,0.1457368,0.01096451,0.00001317371,0.001220511,0.0001092596,0.006062806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3480406,"threshold_uncertainty_score":0.8222974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04397409456175669,"score_gpt":0.2574356656123766,"score_spread":0.2134615710506199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}