{"id":"W1991906262","doi":"10.1016/j.bbrc.2010.02.040","title":"An antiviral disulfide compound blocks interaction between arenavirus Z protein and cellular promyelocytic leukemia protein","year":2010,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Fundación Bunge y Born; U.S. Public Health Service; Universidad de Buenos Aires; Agencia Nacional de Promoción Científica y Tecnológica; Consejo Nacional de Investigaciones Científicas y Técnicas; National Science Council; Leukemia and Lymphoma Society","keywords":"Promyelocytic leukemia protein; Arenavirus; Lymphocytic choriomeningitis; Transfection; Biology; Acute promyelocytic leukemia; Virology; Mutant; Cytoplasm; Chemistry; Molecular biology; Cell biology; Cell culture; Biochemistry; In vitro; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002769317,0.0003123269,0.0002725706,0.0001792632,0.0002633875,0.0001743481,0.0004291575,0.0003768397,0.001820629],"category_scores_gemma":[0.0002308333,0.0001403235,0.0001817757,0.0001421894,0.0002918065,0.0002420883,0.0001814994,0.0005446751,0.0002004241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003086316,"about_ca_system_score_gemma":0.0003210644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004819774,"about_ca_topic_score_gemma":0.0005142431,"domain_scores_codex":[0.9998654,0.00004464826,0.00001209027,0.0000178371,0.00002062445,0.00003940312],"domain_scores_gemma":[0.9998548,0.00005697456,0.00002491963,0.00001609458,0.0000126353,0.00003456394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000702467,0.00009291592,0.0001762039,0.00003656625,0.00001663024,0.00007409196,0.00002202023,0.00008335509,0.9974892,0.000305402,0.00006844647,0.0009325139],"study_design_scores_gemma":[0.0001007923,0.0005588332,0.000576949,0.000001951779,0.00001262673,0.000110022,0.00001365708,0.0003709891,0.9975858,0.0000418744,0.0006242651,0.000002241656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982956,0.0003434834,0.0004601352,0.00005241243,0.00002559847,0.00001770736,0.00006039189,0.00002169061,0.0007229187],"genre_scores_gemma":[0.9980806,0.0002310638,0.0005865628,0.00004645579,0.00001524041,0.00001252572,0.0002256335,0.000007705697,0.0007942107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001820629,"threshold_uncertainty_score":0.006090581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07306708754569534,"score_gpt":0.4021925124200404,"score_spread":0.3291254248743451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}