{"id":"W1991906262","doi":"10.1016/j.bbrc.2010.02.040","title":"An antiviral disulfide compound blocks interaction between arenavirus Z protein and cellular promyelocytic leukemia protein","year":2010,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Fundación Bunge y Born; U.S. Public Health Service; Universidad de Buenos Aires; Agencia Nacional de Promoción Científica y Tecnológica; Consejo Nacional de Investigaciones Científicas y Técnicas; National Science Council; Leukemia and Lymphoma Society","keywords":"Promyelocytic leukemia protein; Arenavirus; Lymphocytic choriomeningitis; Transfection; Biology; Acute promyelocytic leukemia; Virology; Mutant; Cytoplasm; Chemistry; Molecular biology; Cell biology; Cell culture; Biochemistry; In vitro; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006478001,0.0001855503,0.0002959544,0.0001961743,0.0006508951,0.0002050343,0.0003850408,0.0002152638,0.00002633443],"category_scores_gemma":[0.0003489018,0.0001456972,0.00007077726,0.0005270486,0.001807899,0.0002148774,0.0005421639,0.002239123,0.00003182447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001132768,"about_ca_system_score_gemma":0.0002228316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007058857,"about_ca_topic_score_gemma":0.00003538953,"domain_scores_codex":[0.9980049,0.0002620931,0.0002897285,0.0004516885,0.0005204644,0.0004711411],"domain_scores_gemma":[0.9977345,0.0002539288,0.00004715246,0.001080341,0.0003769775,0.0005071079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073553,0.0004598842,0.0008676456,0.00007942088,0.00003030141,0.000005947918,0.00004807891,9.332108e-9,0.9834661,0.001092222,0.00007833964,0.01376463],"study_design_scores_gemma":[0.0007817754,0.0008550728,0.00650394,0.0001957775,0.00003462547,0.00002314337,0.0001318663,0.002995981,0.9826789,0.001496034,0.004076203,0.0002266171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947919,0.00009866109,0.0000558605,0.002816221,0.00001137678,0.001242127,0.00003064071,0.00006847055,0.0008847117],"genre_scores_gemma":[0.99744,0.0000503133,0.001363382,0.00001556513,0.0002782511,0.0002865292,0.0001782163,0.00002344657,0.0003642557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01353801,"threshold_uncertainty_score":0.9728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07306708754569534,"score_gpt":0.4021925124200404,"score_spread":0.3291254248743451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}