{"id":"W1991922220","doi":"10.1210/en.2012-1962","title":"Phosphorylation of IGFBP-1 at Discrete Sites Elicits Variable Effects on IGF-I Receptor Autophosphorylation","year":2013,"lang":"en","type":"article","venue":"Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Autophosphorylation; Phosphorylation; Endocrinology; Internal medicine; Receptor; Chemistry; Biology; Medicine; Cell biology; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026024,0.0003064242,0.0002228029,0.00009673313,0.0001043789,0.0002609456,0.0001800684,0.0001506181,0.0009196342],"category_scores_gemma":[0.000107852,0.0001168541,0.0002741801,0.00009135773,0.0001386441,0.0001038921,0.0001562093,0.000407867,0.0002915929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002615377,"about_ca_system_score_gemma":0.0001213468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009379543,"about_ca_topic_score_gemma":0.001250522,"domain_scores_codex":[0.9998877,0.00001622582,0.00001239197,0.00001894906,0.00003475109,0.00002994441],"domain_scores_gemma":[0.999909,0.00001573005,0.00003243128,0.000009806151,0.00001097697,0.00002202978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006921688,0.00001046203,0.0001164708,0.00001399115,0.000003129476,0.00001984514,0.000003912147,0.00002201613,0.9994313,0.00001387319,0.0000116236,0.0002841158],"study_design_scores_gemma":[0.0000110672,0.0002382274,0.005288076,0.000003481151,0.00001212395,0.0002621271,0.00001979571,0.0007315644,0.9925873,0.00001726171,0.0008233032,0.000005727069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975162,0.0007835071,0.0009208629,0.00004857963,0.00002006737,0.000008885591,0.0001925063,0.00002584724,0.0004835302],"genre_scores_gemma":[0.9971372,0.0004296491,0.001314478,0.00003796237,0.000005630421,0.00001123281,0.0003496874,0.00001183892,0.0007024247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009379543,"threshold_uncertainty_score":0.003076494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01017996844976505,"score_gpt":0.2382670765178633,"score_spread":0.2280871080680983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}