{"id":"W1991965466","doi":"10.1093/oxfordjournals.schbul.a006988","title":"Monozygotic Twins Exhibit Numerous Epigenetic Differences: Clues to Twin Discordance?","year":2003,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":312,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; Centre for Addiction and Mental Health; McMaster University; University of Toronto","funders":"National Institute of Mental Health; Crohn's and Colitis Foundation; Beckman Research Institute, City of Hope; University of Toronto; National Alliance for Research on Schizophrenia and Depression; Crohn's and Colitis Foundation of Canada","keywords":"Epigenetics; DNA methylation; Monozygotic twin; Genetics; Biology; Twin study; Zygosity; Methylation; Gene; Gene expression; Heritability","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003006443,0.0003604307,0.0003030099,0.00009629037,0.0001831685,0.0000874919,0.0003322808,0.0001885049,0.0003492285],"category_scores_gemma":[0.0002866511,0.0003418426,0.0001518648,0.0002038539,0.00008203067,0.000002637185,0.0001183568,0.0001514706,0.0004712146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002544504,"about_ca_system_score_gemma":0.00009535938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003202194,"about_ca_topic_score_gemma":0.00006842746,"domain_scores_codex":[0.99778,0.0002233752,0.000424422,0.0007614031,0.0002648322,0.0005460239],"domain_scores_gemma":[0.9987637,0.00003450149,0.0001157163,0.0007069948,0.00008060133,0.0002984176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008314485,0.0005420758,0.0275876,0.00008937821,0.0001886398,0.00003157858,0.0003483292,0.001802378,0.9378344,0.003272228,0.00863404,0.01883784],"study_design_scores_gemma":[0.002360511,0.001410648,0.0387119,0.0001018356,0.00008194285,0.00001829709,0.0001619936,0.00003571485,0.610148,0.005298962,0.3402054,0.001464849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823992,0.003328276,0.009884868,0.0006987845,0.000433832,0.0004351859,0.00002295988,0.00003708537,0.00275986],"genre_scores_gemma":[0.984001,0.0003792176,0.0125712,0.0003943791,0.0003034042,0.00008532333,0.00004906211,0.00006376529,0.002152661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3315713,"threshold_uncertainty_score":0.9999034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01184004690110788,"score_gpt":0.2378801969021227,"score_spread":0.2260401500010149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}