{"id":"W1991992681","doi":"10.1016/j.tet.2007.05.030","title":"Ruthenium-catalyzed [2+2] cycloadditions between substituted alkynes and norbornadiene: a theoretical study","year":2007,"lang":"en","type":"article","venue":"Tetrahedron","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Guelph","keywords":"Chemistry; Norbornadiene; Alkyne; Steric effects; Cycloaddition; Intramolecular force; Photochemistry; Ruthenium; Catalysis; Medicinal chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003786411,0.0002784023,0.00032885,0.0001562494,0.000276293,0.00006512016,0.0002435018,0.000173936,0.00126166],"category_scores_gemma":[0.0002400716,0.0002708115,0.000092392,0.0003163107,0.0004819261,0.0001650549,0.0001001606,0.0003969477,0.0001421185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001466868,"about_ca_system_score_gemma":0.00005551248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002826452,"about_ca_topic_score_gemma":0.0003785159,"domain_scores_codex":[0.9982111,0.00001585706,0.0004322589,0.0004886931,0.0003274034,0.0005247078],"domain_scores_gemma":[0.9982881,0.0006170198,0.00009561057,0.000610868,0.00006912807,0.0003192642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006117417,0.006221477,0.4560165,0.0004021207,0.002366872,0.0009991875,0.01275503,0.000009751493,0.3308711,0.1008023,0.001691177,0.08725269],"study_design_scores_gemma":[0.009717731,0.0002867921,0.7539124,0.0002386021,0.002323275,0.0007378513,0.01620389,0.0001779466,0.183213,0.01261846,0.0175441,0.003025978],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786121,0.00009321346,0.0003724656,0.0001316051,0.00009424364,0.000209478,0.0001704991,0.0003084421,0.02000794],"genre_scores_gemma":[0.9987924,0.00001070057,0.000171504,0.00001068517,0.0003984824,0.00002831353,0.0002477431,0.00004537635,0.0002948727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2978959,"threshold_uncertainty_score":0.9999744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01111372014108208,"score_gpt":0.2642582526050934,"score_spread":0.2531445324640113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}