{"id":"W1991994537","doi":"10.1002/jps.21347","title":"Nanoparticulate biopolymers deliver insulin orally eliciting pharmacological response","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Insulin; Pharmacology; Medicine; Chemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005373017,0.0003771426,0.0006206679,0.0003743939,0.001024642,0.00004441011,0.0009724519,0.0002975248,0.002065501],"category_scores_gemma":[0.0009166304,0.0002834876,0.0003261576,0.001077111,0.002333394,0.0007657955,0.0001994113,0.001490237,0.0002721357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002101573,"about_ca_system_score_gemma":0.0004180314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006794045,"about_ca_topic_score_gemma":8.308328e-7,"domain_scores_codex":[0.9940562,0.002096091,0.001373515,0.0004532313,0.0009805564,0.001040412],"domain_scores_gemma":[0.9956914,0.001995072,0.0007656642,0.0001249788,0.0004448375,0.000978086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006282941,0.0007502653,0.01095145,0.00002450527,0.0003085112,0.002581756,0.001042274,0.01030947,0.9279851,0.0002907428,0.003790031,0.03568296],"study_design_scores_gemma":[0.007740658,0.002027453,0.004670964,0.00009129971,0.0005243234,0.006726081,0.0009345087,0.02965639,0.6169094,0.0003024646,0.3294219,0.0009945286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883239,0.004297161,0.0004084248,0.00275827,0.002513897,0.000294003,0.00001545481,0.00007973672,0.001309173],"genre_scores_gemma":[0.9915802,0.001736542,0.001505392,0.004245762,0.0006677069,0.000008556074,7.12034e-7,0.00002224933,0.0002328988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3256319,"threshold_uncertainty_score":0.9999617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2389594487756639,"score_gpt":0.482809295795879,"score_spread":0.2438498470202151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}