{"id":"W1992053460","doi":"10.1371/journal.ppat.1003722","title":"Hepatitis B Virus Disrupts Mitochondrial Dynamics: Induces Fission and Mitophagy to Attenuate Apoptosis","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":307,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health; Deutsche Forschungsgemeinschaft; University of Southern California","keywords":"Mitophagy; MFN2; Parkin; Mitochondrial fission; PINK1; Biology; Cell biology; Mitochondrion; MFN1; DNAJA3; HBx; mitochondrial fusion; DNM1L; Autophagy; Mitochondrial DNA; Virology; Hepatitis B virus; Apoptosis; Virus; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000358644,0.0002347088,0.000357402,0.0001293834,0.000128414,0.00005160855,0.00009954801,0.0001385318,0.0006725307],"category_scores_gemma":[0.00009955821,0.000194128,0.0001022519,0.0001751868,0.00005343023,0.0001337689,0.00007873933,0.0001444202,0.000516033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006886819,"about_ca_system_score_gemma":0.00004172511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005736631,"about_ca_topic_score_gemma":0.00007234783,"domain_scores_codex":[0.9986136,0.00005556605,0.0002684001,0.0004141154,0.0003009794,0.0003473358],"domain_scores_gemma":[0.9989477,0.00006132593,0.00006858673,0.0003650094,0.0001065434,0.000450854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001237382,0.0003442241,0.0308845,0.00006363147,0.0001587268,0.00005819645,0.0007910979,6.297095e-7,0.9411595,0.00004523802,0.001677343,0.02469311],"study_design_scores_gemma":[0.002867188,0.001120301,0.406646,0.0004312984,0.0004035629,0.00004319477,0.0003184662,0.002531665,0.5829834,0.000850075,0.00105339,0.0007515016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967283,0.0002716743,0.00007779237,0.001062642,0.0003253153,0.0008602368,0.0001520031,0.0001080771,0.0004139625],"genre_scores_gemma":[0.9949412,0.0004133946,0.0015187,0.001741339,0.0005131762,0.0002130488,0.00008009521,0.00004914022,0.0005299437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3757615,"threshold_uncertainty_score":0.791631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296764266939339,"score_gpt":0.2521789470086719,"score_spread":0.2392113043392785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}