{"id":"W1992053460","doi":"10.1371/journal.ppat.1003722","title":"Hepatitis B Virus Disrupts Mitochondrial Dynamics: Induces Fission and Mitophagy to Attenuate Apoptosis","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":307,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health; Deutsche Forschungsgemeinschaft; University of Southern California","keywords":"Mitophagy; MFN2; Parkin; Mitochondrial fission; PINK1; Biology; Cell biology; Mitochondrion; MFN1; DNAJA3; HBx; mitochondrial fusion; DNM1L; Autophagy; Mitochondrial DNA; Virology; Hepatitis B virus; Apoptosis; Virus; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001353577,0.0002776183,0.0002761971,0.0001790293,0.0001470744,0.0001824595,0.0001108472,0.0002538948,0.0007328598],"category_scores_gemma":[0.00008521403,0.0001005537,0.0001788742,0.0001288694,0.0001764002,0.0002078407,0.0001824623,0.0004113602,0.000130241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001773512,"about_ca_system_score_gemma":0.0001561648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002763589,"about_ca_topic_score_gemma":0.0004746809,"domain_scores_codex":[0.9999074,0.00001981033,0.00001077447,0.00001816639,0.00001948357,0.00002450546],"domain_scores_gemma":[0.9999555,0.0000057365,0.00001098831,0.000006801239,0.000004777436,0.00001618377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002986788,0.0001054669,0.00009774642,0.00005968638,0.000006470741,0.00003461093,0.00002086447,0.00005715757,0.9959526,0.0001341643,0.00004596433,0.003186502],"study_design_scores_gemma":[0.0001216898,0.001934002,0.003886383,0.00001503179,0.0000255762,0.000384042,0.00002597867,0.001329208,0.988997,0.00009711145,0.003177217,0.000006872092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934283,0.002696344,0.002249699,0.0001311373,0.00004113161,0.00004324939,0.00008822454,0.0001077597,0.001214134],"genre_scores_gemma":[0.9958438,0.001208745,0.001395307,0.0000489239,0.0000103306,0.00004071203,0.0001354958,0.0000136304,0.001303053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007328598,"threshold_uncertainty_score":0.002451718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296764266939339,"score_gpt":0.2521789470086719,"score_spread":0.2392113043392785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}