{"id":"W1992118938","doi":"10.1079/pns2006505","title":"REducing Deaths due to OXidative Stress (The REDOXS© Study): rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically-ill patients","year":2006,"lang":"en","type":"review","venue":"Proceedings of The Nutrition Society","topic":"Clinical Nutrition and Gastroenterology","field":"Nursing","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"Clinical Evaluation Research Unit; St. Joseph’s Healthcare Hamilton; Kingston General Hospital","funders":"Vedecká Grantová Agentúra MŠVVaŠ SR a SAV","keywords":"Medicine; Glutamine; Randomized controlled trial; Enteral administration; Mechanical ventilation; Intensive care unit; Organ dysfunction; Clinical endpoint; Intensive care medicine; Parenteral nutrition; Medical nutrition therapy; Clinical trial; Internal medicine; Biology; Sepsis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03711113,0.00401052,0.006548158,0.001156195,0.001516461,0.002598379,0.001855239,0.006322013,0.007536088],"category_scores_gemma":[0.03567717,0.001948477,0.007330846,0.001426762,0.002651424,0.001937315,0.001593845,0.003684906,0.001715636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001181231,"about_ca_system_score_gemma":0.003696253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005957079,"about_ca_topic_score_gemma":0.001080874,"domain_scores_codex":[0.9605383,0.03265391,0.002462734,0.001880301,0.001479286,0.0009854073],"domain_scores_gemma":[0.9906867,0.004317845,0.001816956,0.001244607,0.0009958619,0.0009380719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9392418,0.005155374,0.002830283,0.01179566,0.01221099,0.0002106553,0.0001999359,0.001320305,0.003664554,0.003346174,0.002718233,0.01730608],"study_design_scores_gemma":[0.9405908,0.0367315,0.001986957,0.000913255,0.007324472,0.00007531467,0.00005098753,0.001576148,0.000701117,0.002815062,0.007163356,0.00007108338],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.135973,0.01660855,0.01896329,0.007191863,0.006759854,0.8049361,0.003872846,0.0003444612,0.005350235],"genre_scores_gemma":[0.1391169,0.003277489,0.03412113,0.005006177,0.001234967,0.8133337,0.001026748,0.00004916937,0.002833678],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.03711113,"threshold_uncertainty_score":0.1962648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04676290234879006,"score_gpt":0.3634289148382912,"score_spread":0.3166660124895011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}