{"id":"W1992131118","doi":"10.1182/blood-2002-08-2608","title":"Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Hemin; Heme oxygenase; Internal medicine; Endocrinology; Zinc protoporphyrin; Heme; Medicine; Blood pressure; Aorta; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000949839,0.0000928451,0.0001549314,0.00003733063,0.00001361572,0.000003362453,0.00003354751,0.0001098558,0.000009424549],"category_scores_gemma":[0.0001472393,0.00009437426,0.00002568565,0.0000843252,0.00004389176,0.000005948572,0.0000137742,0.0000430737,7.113572e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004384885,"about_ca_system_score_gemma":0.00002846388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009664361,"about_ca_topic_score_gemma":0.00002301666,"domain_scores_codex":[0.9992925,0.00005069263,0.0002281293,0.0002433097,0.00008524574,0.0001001447],"domain_scores_gemma":[0.9996084,0.000006883391,0.0001001998,0.0001738354,0.00007773921,0.00003294368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002654445,0.0001724254,0.007934271,0.0000176445,0.00003098355,7.49921e-7,0.00007255674,0.00001796922,0.9906934,0.000005676885,0.0001847283,0.0008430373],"study_design_scores_gemma":[0.0006444014,0.0001297546,0.007020551,0.00001969197,0.00003432663,0.000004657836,0.0001505653,0.00001730348,0.9914598,0.00006890375,0.0003564681,0.00009361564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975502,0.002054718,0.00003287541,0.00002873794,0.00005899716,0.0001494462,0.00001543834,0.000003850793,0.0001057495],"genre_scores_gemma":[0.9991189,0.0001958134,0.0004195854,0.00001903734,0.00004633744,0.000008770788,0.00008089176,0.00001099748,0.00009972505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001858905,"threshold_uncertainty_score":0.3848471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008491734949206922,"score_gpt":0.2218412157645325,"score_spread":0.2133494808153256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}