{"id":"W1992137702","doi":"10.1016/s0360-3016(01)01596-6","title":"The role of protein kinase B (PKB) in modulating heat sensitivity in a human breast cancer cell line","year":2001,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Protein kinase B; Wortmannin; Apoptosis; Clonogenic assay; Heat shock protein; Transfection; Kinase; Cancer research; Phosphoinositide 3-kinase; PI3K/AKT/mTOR pathway; Cell biology; Molecular biology; Medicine; Signal transduction; Cell culture; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002461589,0.0002446505,0.0003129444,0.0002690094,0.0003473119,0.0005139834,0.0002289588,0.0003548605,0.001215582],"category_scores_gemma":[0.0002281375,0.0002059077,0.000257457,0.0003282521,0.0002200276,0.000316104,0.0001836443,0.00068027,0.0004048424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003342573,"about_ca_system_score_gemma":0.0002209463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001370137,"about_ca_topic_score_gemma":0.001269632,"domain_scores_codex":[0.9998369,0.00004858491,0.00001796408,0.00002573216,0.00003382473,0.00003688824],"domain_scores_gemma":[0.9998542,0.00006301468,0.00001503091,0.00003068789,0.00001730388,0.00001982493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003353296,0.00006728011,0.0003108616,0.00004573601,0.00000880748,0.00004328625,0.0000248096,0.0001423061,0.9978058,0.00009871142,0.00006086459,0.001056184],"study_design_scores_gemma":[0.00002972271,0.0004828234,0.004689483,0.000005684744,0.00002107599,0.0002372531,0.00004287186,0.001222977,0.9914329,0.000050766,0.001778295,0.000006215571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912641,0.004119452,0.001998055,0.0002824387,0.00005665925,0.00003825535,0.0007786424,0.00007024744,0.001392249],"genre_scores_gemma":[0.9942762,0.001730585,0.001749518,0.00004562837,0.0000130124,0.00003324572,0.0008452136,0.00001990089,0.001286757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001370137,"threshold_uncertainty_score":0.004066527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305356635371044,"score_gpt":0.3306936777310759,"score_spread":0.3176401113773654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}