{"id":"W1992169907","doi":"10.1371/journal.pone.0043330","title":"Agonistic and Antagonistic Roles for TNIK and MINK in Non-Canonical and Canonical Wnt Signalling","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Wnt signaling pathway; Biology; Protein kinase domain; Cell biology; Signal transduction; LRP6; LRP5; Kinase; Xenopus; Genetics; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001921,0.0003790442,0.0001752168,0.0001964498,0.0001730728,0.0005023413,0.0002309892,0.0002082114,0.001134308],"category_scores_gemma":[0.0001224418,0.0001634868,0.000267705,0.00009809528,0.0002680286,0.0003413595,0.0003221898,0.0002896139,0.0003593802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004474748,"about_ca_system_score_gemma":0.0002679453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003578194,"about_ca_topic_score_gemma":0.0006741218,"domain_scores_codex":[0.9998025,0.00003039858,0.00001646983,0.00004270911,0.00004898655,0.00005900921],"domain_scores_gemma":[0.9999052,0.000008744542,0.00003020807,0.000008280002,0.00000859768,0.00003904479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002272929,0.0000106597,0.000485649,0.00004349282,0.000004315767,0.0001042968,0.00001388034,0.00005494379,0.9969687,0.0007784577,0.00001699303,0.001291473],"study_design_scores_gemma":[0.00005083807,0.0002513154,0.02080752,0.00001462668,0.00002726863,0.001906626,0.00008204837,0.001201413,0.9706176,0.0003395031,0.004688374,0.00001282072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813411,0.01086122,0.002645544,0.0001354754,0.00003368994,0.00002146443,0.000149037,0.00002906978,0.004783353],"genre_scores_gemma":[0.9943176,0.001946572,0.001372473,0.00004412972,0.000009092364,0.00001403865,0.0001676611,0.000007796894,0.0021206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134308,"threshold_uncertainty_score":0.003794611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02769128600560598,"score_gpt":0.2431308326252389,"score_spread":0.215439546619633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}