{"id":"W1992197029","doi":"10.1016/s0167-4889(01)00168-9","title":"Interactions between regulatory and catalytic subunits of the Candida albicans cAMP-dependent protein kinase are modulated by autophosphorylation of the regulatory subunit","year":2002,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Autophosphorylation; Protein subunit; Phosphorylation; Biochemistry; Gi alpha subunit; Protein kinase A; Tetramer; Mutant; Candida albicans; Recombinant DNA; Interleukin 10 receptor, alpha subunit; Biology; Gamma-aminobutyric acid receptor subunit alpha-1; Kinase; Chemistry; Molecular biology; Enzyme; G alpha subunit","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003312082,0.0003302188,0.0002168684,0.0002576058,0.0003574392,0.000739574,0.0004561689,0.0003164924,0.001112315],"category_scores_gemma":[0.0008549917,0.000273213,0.0002587859,0.0001453033,0.0003654233,0.0003474988,0.0003002987,0.0007057929,0.0005098794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005431429,"about_ca_system_score_gemma":0.0002553293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005726295,"about_ca_topic_score_gemma":0.0006625178,"domain_scores_codex":[0.9996824,0.00006282481,0.00001611629,0.00006126573,0.00007843543,0.00009894302],"domain_scores_gemma":[0.9995696,0.0001542846,0.0000847321,0.00005023529,0.00003849452,0.0001027111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004629327,0.00006239952,0.000700766,0.00002985454,0.00001140743,0.0001419556,0.00005496235,0.00009992283,0.9953842,0.0007390913,0.0001058472,0.002206716],"study_design_scores_gemma":[0.000118444,0.0002748847,0.02580261,0.00002054816,0.00005750813,0.00134232,0.00018355,0.006379171,0.9619814,0.0008371873,0.00297566,0.00002679789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954637,0.001597405,0.001021554,0.0001036648,0.00003632013,0.000008997445,0.00003505641,0.0000374993,0.001695934],"genre_scores_gemma":[0.9983711,0.0003315725,0.0004626572,0.00004394543,0.00001309232,0.000007415318,0.0001260911,0.00001188331,0.0006322795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001112315,"threshold_uncertainty_score":0.003940821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03094496092409038,"score_gpt":0.2853642423428606,"score_spread":0.2544192814187702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}