{"id":"W1992199975","doi":"10.1002/jcp.10389","title":"EGF mediates protection against Fas‐induced apoptosis by depleting and oxidizing intracellular GSH stocks","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Glutathione; Apoptosis; Programmed cell death; Intracellular; Biology; Epidermal growth factor; Reactive oxygen species; Cell biology; Caspase; Biochemistry; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005537051,0.0001909582,0.0002868727,0.00008497018,0.0001362669,0.00002471455,0.0001111441,0.0002385356,0.00001731922],"category_scores_gemma":[0.0002754539,0.000173862,0.0001275462,0.00009270787,0.00006660334,0.00001285006,0.00004119609,0.0002559611,0.000002167222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002180692,"about_ca_system_score_gemma":0.00006978305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004121064,"about_ca_topic_score_gemma":9.735729e-7,"domain_scores_codex":[0.9985768,0.0003084026,0.0004497191,0.0002506931,0.0001527261,0.0002617253],"domain_scores_gemma":[0.9990479,0.00002045428,0.0004813036,0.0001591916,0.0001623333,0.0001288139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006308848,0.00005113611,0.00003385269,0.00002574056,0.00006712985,0.000003314462,0.00003959003,0.0001106241,0.9975013,0.0000693007,0.000116568,0.001918321],"study_design_scores_gemma":[0.0006908796,0.0003532875,0.00004655491,0.00003491029,0.00002777425,0.00003736356,0.000108158,0.0001660265,0.9919665,0.0002778992,0.006104584,0.0001860281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797452,0.003014983,0.01669756,0.00009501226,0.0001839337,0.0001865119,0.000002367402,0.000007315534,0.00006713198],"genre_scores_gemma":[0.998112,0.000245213,0.001115128,0.0001276914,0.0002994258,0.000009200379,0.00002161978,0.00002675911,0.00004296169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01836682,"threshold_uncertainty_score":0.7089887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009863084919767619,"score_gpt":0.2133493154952114,"score_spread":0.2034862305754438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}