{"id":"W1992217226","doi":"10.1371/journal.pmed.1001250","title":"HIV Treatment as Prevention: Considerations in the Design, Conduct, and Analysis of Cluster Randomized Controlled Trials of Combination HIV Prevention","year":2012,"lang":"en","type":"review","venue":"PLoS Medicine","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Wellcome Trust; U.S. President’s Emergency Plan for AIDS Relief; Bill and Melinda Gates Foundation","keywords":"Psychological intervention; Randomized controlled trial; Medicine; Interim analysis; Interim; Population; Research design; Environmental health; Statistics; Surgery; Psychiatry; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01595672,0.0004057928,0.01367915,0.001881719,0.00006645758,0.00001585742,0.0001099947,0.0002244724,0.002761567],"category_scores_gemma":[0.01832597,0.0001838751,0.00283321,0.0009064946,0.0004509255,0.0001067066,0.0000267853,0.0002757583,0.00001073204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001242427,"about_ca_system_score_gemma":0.0004379672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005030994,"about_ca_topic_score_gemma":0.00003544341,"domain_scores_codex":[0.9822275,0.01214325,0.004302462,0.0003130991,0.0007700039,0.0002436558],"domain_scores_gemma":[0.9798174,0.0166498,0.002433812,0.0005088492,0.000444079,0.0001460589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.104584,0.024076,0.0002397411,0.05079425,0.27668,0.00008911653,0.009741532,0.000009674566,0.0002393516,0.01870564,0.0312315,0.4836092],"study_design_scores_gemma":[0.5560772,0.007789214,0.00002590905,0.03641479,0.3717469,0.00008242821,0.0006410924,0.001937908,0.00004574103,0.001947408,0.0230051,0.0002863575],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001439354,0.9753007,0.002724461,0.00221799,0.00004384344,0.01732175,0.00008021046,0.00001251394,0.002154547],"genre_scores_gemma":[0.003882273,0.9803999,0.0003572727,0.00003390808,0.0001505707,0.00312162,0.001665889,0.00002564162,0.01036291],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4833229,"threshold_uncertainty_score":0.9981501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2885876634870158,"score_gpt":0.4732146504474702,"score_spread":0.1846269869604544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}