{"id":"W1992263392","doi":"10.1371/journal.pone.0022702","title":"Culture Enriched Molecular Profiling of the Cystic Fibrosis Airway Microbiome","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tracheal and airway disorders","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Microbiome; Biology; Metagenomics; Cystic fibrosis; Terminal restriction fragment length polymorphism; Microbiology; Pseudomonas aeruginosa; Obligate anaerobe; Microbiological culture; Human Microbiome Project; Respiratory tract; Obligate; Computational biology; Human microbiome; Genetics; Bacteria; Gene; Restriction fragment length polymorphism; Respiratory system; Polymerase chain reaction; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005079856,0.0001020564,0.0002146125,0.00003214396,0.00003493463,0.000002686539,0.0001121285,0.00007658482,0.0001053795],"category_scores_gemma":[0.00006760725,0.00006348965,0.00009768573,0.0002116621,0.00007495416,0.0000246104,0.00003667496,0.0001471572,0.00002905185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001422071,"about_ca_system_score_gemma":0.00003310054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002582016,"about_ca_topic_score_gemma":0.00000166278,"domain_scores_codex":[0.9993145,0.00002456358,0.0001682687,0.0001472202,0.0001825009,0.0001629138],"domain_scores_gemma":[0.9995267,0.000009767058,0.00006687874,0.0002579986,0.00008146311,0.00005718962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006460254,0.001179799,0.005099203,0.0004006072,0.0001422021,0.000002598163,0.0008258558,3.948538e-7,0.9919368,0.0001312774,0.00004963001,0.0001669989],"study_design_scores_gemma":[0.0005927292,0.0002282695,0.008952274,0.0002614612,0.0003558173,0.000002799497,0.0001750486,0.00002945271,0.9891256,0.000162169,0.00002951072,0.0000848798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943106,0.0007546969,0.0001094751,0.000334408,0.00002275393,0.0004031925,0.00001279933,0.00004287103,0.004009158],"genre_scores_gemma":[0.9850047,0.00001997909,0.01383687,0.000205117,0.00002301961,0.00001583435,0.000011194,0.00001672747,0.0008665968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01372739,"threshold_uncertainty_score":0.2589033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03030670444943329,"score_gpt":0.2138814211689432,"score_spread":0.1835747167195099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}