{"id":"W1992263392","doi":"10.1371/journal.pone.0022702","title":"Culture Enriched Molecular Profiling of the Cystic Fibrosis Airway Microbiome","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tracheal and airway disorders","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Microbiome; Biology; Metagenomics; Cystic fibrosis; Terminal restriction fragment length polymorphism; Microbiology; Pseudomonas aeruginosa; Obligate anaerobe; Microbiological culture; Human Microbiome Project; Respiratory tract; Obligate; Computational biology; Human microbiome; Genetics; Bacteria; Gene; Restriction fragment length polymorphism; Respiratory system; Polymerase chain reaction; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003326005,0.0003989595,0.0004239387,0.0005251652,0.0002907188,0.0006412654,0.0002379933,0.0004501802,0.0003771064],"category_scores_gemma":[0.0008336858,0.0002030065,0.0004165104,0.0005637156,0.0002435526,0.0002675861,0.0006275483,0.0004739756,0.0003183068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001186474,"about_ca_system_score_gemma":0.0001736539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001003739,"about_ca_topic_score_gemma":0.001599569,"domain_scores_codex":[0.9995252,0.00009105874,0.00003976639,0.0001097117,0.0001594202,0.00007483669],"domain_scores_gemma":[0.9996222,0.0001037243,0.00007084373,0.0000336446,0.0001305113,0.0000390075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003940302,0.00002948759,0.003448223,0.00004221703,0.0000113416,0.00005066445,0.0001044806,0.0002370161,0.9933848,0.00001771797,0.00003659176,0.002597939],"study_design_scores_gemma":[0.00001004384,0.0007604436,0.1242671,0.00005424627,0.0001236044,0.0008206538,0.0007285916,0.008931545,0.8601524,0.0001567148,0.003944097,0.00005060839],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809232,0.0008441038,0.01541489,0.000117828,0.00003054453,0.0001079946,0.00159635,0.0001149964,0.0008501609],"genre_scores_gemma":[0.9353592,0.001523413,0.05613624,0.0003885958,0.00003496301,0.0001835183,0.00490392,0.00008539719,0.001384735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001003739,"threshold_uncertainty_score":0.001995802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03030670444943329,"score_gpt":0.2138814211689432,"score_spread":0.1835747167195099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}