{"id":"W1992268707","doi":"10.4161/cc.23046","title":"Transgenerational cell fate profiling","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; National Institutes of Health; Institut National Du Cancer","keywords":"Biology; Cell fate determination; Mitosis; Aneuploidy; Carcinogenesis; Cell division; Cell cycle; Cell biology; Cell; Population; Genome instability; Genetics; Cancer research; DNA damage; Gene; Transcription factor; DNA; Chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007613473,0.00008691077,0.00005689419,0.00001336743,0.00006033986,0.00001116068,0.00008144337,0.00008781413,0.00004608662],"category_scores_gemma":[0.000002574786,0.00008640963,0.00005745522,0.00002699954,0.00001817596,0.000003840432,0.00002606408,0.00004945288,0.0000634521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005774291,"about_ca_system_score_gemma":0.00002472968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003107956,"about_ca_topic_score_gemma":0.00000273812,"domain_scores_codex":[0.9994624,0.0000189943,0.00009855619,0.0001414729,0.00005570462,0.0002228572],"domain_scores_gemma":[0.9997208,0.000002547732,0.00002627493,0.000153611,0.00002207909,0.00007464914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007276929,0.00008333242,0.002083078,0.00001421129,0.000004516217,1.949743e-7,0.00003881198,0.0001284071,0.9963629,0.00005808671,0.0009391449,0.0002800532],"study_design_scores_gemma":[0.0002281524,0.00002816169,0.0002846417,0.000001113278,0.000008594548,0.000002184873,0.00002500504,0.000203313,0.9688459,0.00001023195,0.03024335,0.000119344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813393,0.001173956,0.004428954,0.00002051954,0.0001874798,0.00009588259,0.00001443439,0.000009628949,0.01272987],"genre_scores_gemma":[0.9942922,0.00009729654,0.002436949,0.0002192158,0.0004564482,0.00001263354,0.000221643,0.00001761119,0.002246004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0293042,"threshold_uncertainty_score":0.3523683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007716122455714712,"score_gpt":0.2197200353171951,"score_spread":0.2120039128614803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}