{"id":"W1992268707","doi":"10.4161/cc.23046","title":"Transgenerational cell fate profiling","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; National Institutes of Health; Institut National Du Cancer","keywords":"Biology; Cell fate determination; Mitosis; Aneuploidy; Carcinogenesis; Cell division; Cell cycle; Cell biology; Cell; Population; Genome instability; Genetics; Cancer research; DNA damage; Gene; Transcription factor; DNA; Chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001367873,0.0002789874,0.0001780316,0.000317685,0.000145027,0.0003063754,0.0002740418,0.0002689881,0.001157334],"category_scores_gemma":[0.0001603125,0.0001345266,0.0001884518,0.000194078,0.000256302,0.0002223159,0.0002316871,0.0005447567,0.000356319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003646695,"about_ca_system_score_gemma":0.0001787521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006419506,"about_ca_topic_score_gemma":0.0009582489,"domain_scores_codex":[0.9998538,0.00001213051,0.000008086662,0.00005810244,0.00004779372,0.00002002696],"domain_scores_gemma":[0.9998707,0.00002958945,0.00003747591,0.0000262082,0.0000184699,0.00001763387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001444909,0.000006909804,0.0001386564,0.00001346625,0.000001588164,0.00001517322,0.00001232735,0.00034349,0.9965909,0.0004946041,0.00002647894,0.002341974],"study_design_scores_gemma":[0.000003087954,0.00007200448,0.001305023,0.000002920829,0.000008792041,0.00008831416,0.00001155384,0.007771705,0.9878492,0.0002494406,0.002632438,0.000005510977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7749044,0.0008621312,0.2164062,0.0001260272,0.00006019378,0.0001834584,0.002208829,0.0009090271,0.004339699],"genre_scores_gemma":[0.956705,0.0007089481,0.03601694,0.00006026374,0.00000799175,0.0001033025,0.001157093,0.00009433954,0.005146085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001157334,"threshold_uncertainty_score":0.003871679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007716122455714712,"score_gpt":0.2197200353171951,"score_spread":0.2120039128614803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}