{"id":"W1992305636","doi":"10.1128/jvi.78.22.12288-12296.2004","title":"CXCR4-Dependent Infection of CD8 <sup>+</sup> , but Not CD4 <sup>+</sup> , Lymphocytes by a Primary Human Immunodeficiency Virus Type 1 Isolate","year":2004,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Université Laval; University of Washington; University of Pennsylvania","keywords":"Biology; CD8; Virology; Virus; Phenotype; CXCR4; Viral replication; Genotype; T lymphocyte; Molecular biology; Immunology; Antigen; Immune system; Gene; Genetics; Chemokine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108509,0.0002198395,0.0002035641,0.00006211692,0.00009731685,0.0002364884,0.0001562003,0.0001213203,0.000869054],"category_scores_gemma":[0.0001262579,0.0001031713,0.000171167,0.0000722449,0.00009731833,0.00008525312,0.0001176091,0.0004758611,0.0003375217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693578,"about_ca_system_score_gemma":0.0001367595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006245197,"about_ca_topic_score_gemma":0.0007462534,"domain_scores_codex":[0.9998592,0.00003159613,0.00001510466,0.00002356841,0.00003220781,0.00003825753],"domain_scores_gemma":[0.9999298,0.00002078466,0.00001251358,0.00001428589,0.000009764211,0.00001280039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001157344,0.00002247244,0.0003184229,0.00002107695,0.000003341008,0.0000535661,0.00001724243,0.00004076089,0.9984912,0.00004867087,0.0000373747,0.0008301854],"study_design_scores_gemma":[0.00004212919,0.0009489512,0.008829973,0.00000749544,0.00002187383,0.0008062458,0.0000323762,0.001339137,0.9859325,0.00003891824,0.001995264,0.000005081321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985234,0.0003194302,0.0004166155,0.00002145957,0.000007741214,0.00001829247,0.0001587401,0.00001194319,0.0005223114],"genre_scores_gemma":[0.9956883,0.0002917715,0.0018529,0.00003924509,0.00001302881,0.00005138989,0.000857443,0.0000106157,0.001195436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000869054,"threshold_uncertainty_score":0.002907336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01260709056635993,"score_gpt":0.2601823646269856,"score_spread":0.2475752740606257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}